A
Angela Carballedo
Researcher at Trinity College, Dublin
Publications - 51
Citations - 3756
Angela Carballedo is an academic researcher from Trinity College, Dublin. The author has contributed to research in topics: Major depressive disorder & rs6265. The author has an hindex of 26, co-authored 48 publications receiving 2824 citations. Previous affiliations of Angela Carballedo include Boston Children's Hospital & University of Regensburg.
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Journal ArticleDOI
Cortical abnormalities in adults and adolescents with major depression based on brain scans from 20 cohorts worldwide in the ENIGMA Major Depressive Disorder Working Group.
Lianne Schmaal,Derrek P. Hibar,Philipp G. Sämann,Geoffrey B. Hall,Bernhard T. Baune,Neda Jahanshad,Joshua W. Cheung,T.G.M. van Erp,Daniel Bos,M. A. Ikram,Meike W. Vernooij,Wiro J. Niessen,Wiro J. Niessen,Henning Tiemeier,Henning Tiemeier,A. Hofman,Katharina Wittfeld,Hans-Jörgen Grabe,Hans-Jörgen Grabe,Deborah Janowitz,Robin Bülow,M Selonke,Henry Völzke,Dominik Grotegerd,Udo Dannlowski,Udo Dannlowski,Volker Arolt,Nils Opel,Walter Heindel,Harald Kugel,D. Hoehn,Michael Czisch,Baptiste Couvy-Duchesne,Baptiste Couvy-Duchesne,Miguel E. Rentería,Lachlan T. Strike,Margaret J. Wright,Natalie T. Mills,Natalie T. Mills,G.I. de Zubicaray,Katie L. McMahon,Sarah E. Medland,Nicholas G. Martin,Nathan A. Gillespie,Roberto Goya-Maldonado,Oliver Gruber,Bernd Krämer,Sean N. Hatton,Jim Lagopoulos,Ian B. Hickie,Thomas Frodl,Thomas Frodl,Angela Carballedo,Eva-Maria Frey,L. S. van Velzen,B.W.J.H. Penninx,M-J van Tol,N.J. van der Wee,Christopher G. Davey,Ben J. Harrison,Benson Mwangi,Bo Cao,Jair C. Soares,Ilya M. Veer,Henrik Walter,D. Schoepf,Bartosz Zurowski,Carsten Konrad,Elisabeth Schramm,Claus Normann,Knut Schnell,Matthew D. Sacchet,Ian H. Gotlib,Glenda MacQueen,Beata R. Godlewska,Thomas Nickson,Andrew M. McIntosh,Andrew M. McIntosh,Martina Papmeyer,Martina Papmeyer,Heather C. Whalley,Jeremy Hall,Jeremy Hall,J.E. Sussmann,Meng Li,Martin Walter,Martin Walter,Lyubomir I. Aftanas,Ivan Brack,Nikolay A. Bokhan,Nikolay A. Bokhan,Nikolay A. Bokhan,Paul M. Thompson,Dick J. Veltman +93 more
TL;DR: In this article, the authors present the largest ever worldwide study by the ENIGMA (Enhancing Neuro Imaging Genetics through Meta-Analysis) Major Depressive Disorder Working Group on cortical structural alterations in MDD.
Subcortical brain alterations in major depressive disorder: findings from the ENIGMA Major Depressive Disorder working group
Lianne Schmaal,Dick J. Veltman,T.G.M. van Erp,Philipp G. Sämann,Thomas Frodl,Neda Jahanshad,Elizabeth Loehrer,Henning Tiemeier,A. Hofman,Wiro J. Niessen,Meike W. Vernooij,M. A. Ikram,Katharina Wittfeld,Hans-Jörgen Grabe,Andrea Block,K Hegenscheid,Henry Völzke,D. Hoehn,Michael Czisch,Jim Lagopoulos,Sean N. Hatton,Ian B. Hickie,Roberto Goya-Maldonado,Bernhard K. Krämer,Oliver Gruber,Baptiste Couvy-Duchesne,Miguel E. Rentería,Lachlan T. Strike,Natalie T. Mills,G. I. de Zubicaray,Katie L. McMahon,Sarah E. Medland,Nicholas G. Martin,Nathan A. Gillespie,Margaret J. Wright,Geoffrey B. Hall,Glenda MacQueen,Eva-Maria Frey,Angela Carballedo,L. S. van Velzen,M.J.D. van Tol,N.J. van der Wee,Ilya M. Veer,Henrik Walter,Knut Schnell,Elisabeth Schramm,Claus Normann,D. Schoepf,Carsten Konrad,Bartosz Zurowski,Thomas Nickson,Andrew M. McIntosh,Martina Papmeyer,Heather C. Whalley,J.E. Sussmann,Beata R. Godlewska,Philip J. Cowen,Felix Fischer,Matthias Rose,Brenda W.J.H. Penninx,Paul M. Thompson,D. P. Hibar +61 more
TL;DR: In this paper, the authors meta-analyzed three-dimensional brain magnetic resonance imaging data from 1728 major depressive disorder (MDD) patients and 7199 controls from 15 research samples worldwide, to identify subcortical brain volumes that robustly discriminate MDD patients from healthy controls.
Journal ArticleDOI
White matter disturbances in major depressive disorder: a coordinated analysis across 20 international cohorts in the ENIGMA MDD working group
Laura S van Velzen,Sinead Kelly,Sinead Kelly,Dmitry Isaev,André Aleman,Lyubomir I. Aftanas,Jochen Bauer,Bernhard T. Baune,Bernhard T. Baune,Ivan V. Brak,Angela Carballedo,Angela Carballedo,Colm G. Connolly,Colm G. Connolly,Baptiste Couvy-Duchesne,Kathryn R. Cullen,Konstantin V. Danilenko,Udo Dannlowski,Verena Enneking,Elena Filimonova,Katharina Förster,Thomas Frodl,Thomas Frodl,Ian H. Gotlib,Nynke A. Groenewold,Nynke A. Groenewold,Dominik Grotegerd,Mathew A. Harris,Sean N. Hatton,Emma L. Hawkins,Ian B. Hickie,Tiffany C. Ho,Tiffany C. Ho,Andreas Jansen,Tilo Kircher,Bonnie Klimes-Dougan,Peter Kochunov,Axel Krug,Jim Lagopoulos,Renick Lee,Tristram A. Lett,Meng Li,Frank P. MacMaster,Nicholas G. Martin,Andrew M. McIntosh,Quinn McLellan,Quinn McLellan,Susanne Meinert,Igor Nenadic,Evgeny Osipov,Brenda W.J.H. Penninx,Maria J. Portella,Jonathan Repple,Annerine Roos,Matthew D. Sacchet,Philipp G. Sämann,Knut Schnell,Xueyi Shen,Kang Sim,Kang Sim,Dan J. Stein,Marie-José van Tol,Alexander Tomyshev,Leonardo Tozzi,Leonardo Tozzi,Ilya M. Veer,Robert Vermeiren,Robert Vermeiren,Yolanda Vives-Gilabert,Henrik Walter,Martin Walter,Nic J.A. van der Wee,Steven J.A. van der Werff,Melinda Westlund Schreiner,Heather C. Whalley,Margaret J. Wright,Tony T. Yang,Alyssa H. Zhu,Dick J. Veltman,Paul M. Thompson,Neda Jahanshad,Lianne Schmaal +81 more
TL;DR: In this paper, the authors examined WM anisotropy and diffusivity in 1305 MDD patients and 1602 healthy controls (age range 12-88 years) from 20 samples worldwide, which included both adults and adolescents, within the MDD Working Group of the Enhancing Neuroimaging Genetics through Meta-Analysis (ENIGMA) consortium.
Journal ArticleDOI
Functional connectivity of emotional processing in depression
Angela Carballedo,Johanna Scheuerecker,Eva M. Meisenzahl,Veronika Schoepf,Arun L.W. Bokde,Hans-Jürgen Möller,Myles Doyle,Martin Wiesmann,Thomas Frodl,Thomas Frodl +9 more
TL;DR: It could be that there is an emotional processing bias with disconnection bilaterally between amygdala to orbitofrontal cortices and in addition a right disconnection between amygdala and ACC as well as between ACC and prefrontal cortex possibly in line with a more prominent role for the right hemisphere in emotion processing.
Journal ArticleDOI
Reduced expression of glucocorticoid-inducible genes GILZ and SGK-1: high IL-6 levels are associated with reduced hippocampal volumes in major depressive disorder
Thomas Frodl,Angela Carballedo,Martina M. Hughes,Karim Saleh,Andrew J. Fagan,Norbert Skokauskas,Declan M. McLoughlin,James F. Meaney,Veronica O'Keane,Thomas J. Connor +9 more
TL;DR: The findings suggest that childhood maltreatment, peripheral inflammatory and glucocorticoid markers and hippocampal volume are interrelated factors in the pathophysiology of MDD.