S
Stéphanie Blandin
Researcher at University of Strasbourg
Publications - 44
Citations - 5314
Stéphanie Blandin is an academic researcher from University of Strasbourg. The author has contributed to research in topics: Anopheles gambiae & Anopheles. The author has an hindex of 23, co-authored 35 publications receiving 4876 citations. Previous affiliations of Stéphanie Blandin include Centre national de la recherche scientifique & French Institute of Health and Medical Research.
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Journal ArticleDOI
Immunity-Related Genes and Gene Families in Anopheles gambiae
George K. Christophides,Evgeny M. Zdobnov,Carolina Barillas-Mury,Ewan Birney,Stéphanie Blandin,Claudia Blass,Paul T. Brey,Frank H. Collins,Alberto Danielli,George Dimopoulos,Charles Hetru,Ngo Thi Hoa,Jules A. Hoffmann,Stefan M. Kanzok,Ivica Letunic,Elena A. Levashina,Thanasis G. Loukeris,Gareth J Lycett,Stephan Meister,Kristin Michel,Luis F. Moita,Hans-Michael Müller,Mike A. Osta,Susan M. Paskewitz,Jean-Marc Reichhart,Andrey Rzhetsky,Laurent Troxler,Kenneth D. Vernick,Dina Vlachou,Jennifer Volz,Christian von Mering,Jiannong Xu,Liangbiao Zheng,Peer Bork,Fotis C. Kafatos +34 more
TL;DR: 242 Anopheles gambiae genes from 18 gene families implicated in innate immunity are identified and marked diversification relative to Drosophila melanogaster is detected, confirming that sequence diversification is accompanied by specific responses to different immune challenges.
Journal ArticleDOI
Evolutionary Dynamics of Immune-Related Genes and Pathways in Disease-Vector Mosquitoes
Robert M. Waterhouse,Evgenia V. Kriventseva,Stephan Meister,Zhiyong Xi,Kanwal S. Alvarez,Lyric C. Bartholomay,Carolina Barillas-Mury,Guowu Bian,Stéphanie Blandin,Bruce M. Christensen,Yuemei Dong,Haobo Jiang,Michael R. Kanost,Anastasios C. Koutsos,Elena A. Levashina,Jianyong Li,Petros Ligoxygakis,Robert M. MacCallum,George F. Mayhew,António M. Mendes,Kristin Michel,Mike A. Osta,Susan M. Paskewitz,Sang Woon Shin,Dina Vlachou,Lihui Wang,Weiqi Wei,Liangbiao Zheng,Zhen Zou,David W. Severson,Alexander S. Raikhel,Fotis C. Kafatos,George Dimopoulos,Evgeny M. Zdobnov,George K. Christophides +34 more
TL;DR: Analysis of immune signaling pathways and response modules reveals both conservative and rapidly evolving features associated with different functional gene categories and particular aspects of immune reactions, suggesting how innate immunity may have evolved.
Journal ArticleDOI
Complement-like protein TEP1 is a determinant of vectorial capacity in the malaria vector Anopheles gambiae.
Stéphanie Blandin,Shin-Hong Shiao,Luis F. Moita,Chris J. Janse,Andrew P. Waters,Fotis C. Kafatos,Elena A. Levashina +6 more
TL;DR: It is reported that the hemocyte-specific complement-like protein TEP1 from the mosquito Anopheles gambiae binds to and mediates killing of midgut stages of the rodent malaria parasite Plasmodium berghei.
Journal ArticleDOI
Conserved Role of a Complement-like Protein in Phagocytosis Revealed by dsRNA Knockout in Cultured Cells of the Mosquito, Anopheles gambiae
Elena A. Levashina,Luis F. Moita,Stéphanie Blandin,Gert Vriend,Marie Lagueux,Fotis C. Kafatos +5 more
TL;DR: This protein serves as a complement-like opsonin and promotes phagocytosis of some Gram-negative bacteria in a mosquito hemocyte-like cell line and adds substantially to the accumulating evidence of a common ancestry of immune defenses in insects and vertebrates.
Journal ArticleDOI
Highly evolvable malaria vectors: The genomes of 16 Anopheles mosquitoes
Daniel E. Neafsey,Robert M. Waterhouse,Mohammad Reza Abai,Sergey Aganezov,Max A. Alekseyev,James E. Allen,James Amon,Bruno Arcà,Peter Arensburger,Gleb N. Artemov,Lauren A. Assour,Hamidreza Basseri,Aaron M. Berlin,Bruce W. Birren,Stéphanie Blandin,Stéphanie Blandin,Andrew I. Brockman,Thomas R. Burkot,Austin Burt,Clara S. Chan,Cedric Chauve,Joanna C. Chiu,Mikkel B. Christensen,Carlo Costantini,Victoria L.M. Davidson,Elena Deligianni,Tania Dottorini,Vicky Dritsou,Stacey Gabriel,Wamdaogo M. Guelbeogo,Andrew Brantley Hall,Mira V. Han,Thaung Hlaing,Daniel S.T. Hughes,Daniel S.T. Hughes,Adam M. Jenkins,Xiaofang Jiang,Irwin Jungreis,Evdoxia G. Kakani,Evdoxia G. Kakani,Maryam Kamali,Petri Kemppainen,Ryan C. Kennedy,Ioannis K. Kirmitzoglou,Ioannis K. Kirmitzoglou,Lizette L. Koekemoer,Njoroge Laban,Nicholas Langridge,Mara K. N. Lawniczak,Manolis Lirakis,Neil F. Lobo,Ernesto Lowy,Robert M. MacCallum,Chunhong Mao,Gareth Maslen,Charles Mbogo,Jenny McCarthy,Kristin Michel,Sara N. Mitchell,Wendy Moore,Katherine A. Murphy,Anastasia N. Naumenko,Tony Nolan,Eva Maria Novoa,Samantha M. O’Loughlin,Chioma Oringanje,Mohammad Ali Oshaghi,Nazzy Pakpour,Philippos Aris Papathanos,Philippos Aris Papathanos,Ashley Peery,Michael Povelones,Anil Prakash,David P. Price,Ashok Rajaraman,Lisa J. Reimer,David C. Rinker,Antonis Rokas,Tanya L. Russell,N’Fale Sagnon,Maria V. Sharakhova,Terrance Shea,Felipe A. Simão,Felipe A. Simão,Frédéric Simard,Michel A. Slotman,Pradya Somboon,V. N. Stegniy,Claudio J. Struchiner,Claudio J. Struchiner,Gregg W.C. Thomas,Marta Tojo,Pantelis Topalis,Jose M. C. Tubio,Maria F. Unger,John Vontas,Catherine Walton,Craig S. Wilding,Judith H. Willis,Yi-Chieh Wu,Yi-Chieh Wu,Guiyun Yan,Evgeny M. Zdobnov,Evgeny M. Zdobnov,Xiaofan Zhou,Flaminia Catteruccia,Flaminia Catteruccia,George K. Christophides,Frank H. Collins,Robert S. Cornman,Andrea Crisanti,Andrea Crisanti,Martin J. Donnelly,Martin J. Donnelly,Scott J. Emrich,Michael C. Fontaine,Michael C. Fontaine,William M. Gelbart,Matthew W. Hahn,Immo A. Hansen,Paul I. Howell,Fotis C. Kafatos,Manolis Kellis,Daniel Lawson,Christos Louis,Shirley Luckhart,Marc A. T. Muskavitch,Marc A. T. Muskavitch,José M. C. Ribeiro,Michael A. Riehle,Igor V. Sharakhov,Zhijian Tu,Laurence J. Zwiebel,Nora J. Besansky +133 more
TL;DR: The authors investigated the genomic basis of vectorial capacity and explore new avenues for vector control, sequenced the genomes of 16 anopheline mosquito species from diverse locations spanning ~100 million years of evolution Comparative analyses show faster rates of gene gain and loss, elevated gene shuffling on the X chromosome, and more intron losses, relative to Drosophila.