Alexander V. Pavlenko

TL;DR: Taxonomic and functional analysis shows an increased propensity of the gut microbiota to synthesis of the toxic acetaldehyde, suggesting higher risk of colorectal cancer and other pathologies in alcoholics.

TL;DR: Functional analysis of gut microbiota samples from 96 healthy Russian adult subjects shows that the metabolic pathways exhibiting differential abundance in the novel types are primarily associated with the trade-off between the Bacteroidetes and Firmicutes phyla.

TL;DR: This study did not identify a panel of genomic variants common to these elite endurance athlete groups, and since GAMES was underpowered to identify alleles with small effect sizes, some of the suggestive leads identified should be explored in expanded comparisons of world-class endurance athletes and sedentary controls and in tightly controlled exercise training studies.

TL;DR: In this article, an international consortium (GAMES) was established in order to compare elite endurance athletes and ethnicity-matched controls in a case-control study design, which would be useful to understand the differences in the genomic profile of highly trained endurance athletes of world class caliber and sedentary controls.

TL;DR: The data show that the NFIA-AS2 rs1572312, TSHR rs7144481 and RBFOX1 rs7191721 polymorphisms are associated with aerobic performance and elite endurance athlete status.