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Alexis Elbaz
Researcher at Université Paris-Saclay
Publications - 234
Citations - 31979
Alexis Elbaz is an academic researcher from Université Paris-Saclay. The author has contributed to research in topics: Population & Medicine. The author has an hindex of 69, co-authored 205 publications receiving 27260 citations. Previous affiliations of Alexis Elbaz include King's College London & French Institute of Health and Medical Research.
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Mortality in patients with Parkinson's disease treated by stimulation of the subthalamic nucleus.
Michael Schüpbach,Marie-Laure Welter,A. M. Bonnet,Alexis Elbaz,Brandon R. Grossardt,Valérie Mesnage,Jean-Luc Houeto,David Maltête,Luc Mallet,Walter A. Rocca,Alain Mallet,Yves Agid +11 more
TL;DR: Subthalamic nucleus (STN) stimulation improves motor disability and quality of life in patients with advanced Parkinson's disease (PD) and based on a historical comparison of 118 operated patients with 39 nonoperated patients from a different population, survival among operated patients was not better.
Journal ArticleDOI
Changing mortality for motor neuron disease in France (1968–2007): an age-period-cohort analysis
Paul H. Gordon,Fanny Artaud,Albertine Aouba,Françoise Laurent,Vincent Meininger,Alexis Elbaz +5 more
TL;DR: Mortality rates for MND increased between 1968 and 2007, and more rapidly in women than men, and this increase was better explained by the birth-cohort of individuals than by period effects.
Journal ArticleDOI
Cumulative associations between midlife health behaviors and physical functioning in early old age: a 17-year prospective cohort study.
Séverine Sabia,Alexis Elbaz,Nicolas Rouveau,Eric J. Brunner,Mika Kivimäki,Archana Singh-Manoux +5 more
TL;DR: To examine cumulative associations between midlife health behaviors and walking speed and upper‐limb strength in early old age, a large number of studies have found associations between these behaviors and mortality in midlife are positive.
Journal ArticleDOI
A diagnostic flow chart for POLG-related diseases based on signs sensitivity and specificity
Maya Tchikviladzé,Mylène Gilleron,Thierry Maisonobe,Damien Galanaud,Pascal Laforêt,Alexandra Durr,Bruno Eymard,Fanny Mochel,Hélène Ogier,Anthony Behin,Tanya Stojkovic,Bertrand Degos,Isabelle Gourfinkel-An,Frédéric Sedel,Mathieu Anheim,Alexis Elbaz,Karine Viala,Marie Vidailhet,Alexis Brice,Claude Jardel,Anne Lombès +20 more
TL;DR: High sensitivity but low specificity was observed with single signs such as axonal sensory neuropathy, cerebellar syndrome, movement disorders and weakness involving ocular, pharyngeal, axial and/or limb muscles and Phenotypes associated with POLG mutations follow a reproducible pattern, which allows establishing a diagnostic flow chart.
Protective effect of LRRK2 p.R1398H on risk of Parkinson's disease is independent of MAPT and SNCA variants.
Michael G. Heckman,Alexis Elbaz,Owen A. Ross,Matthew J. Farrer,Demetrius M. Maraganore,Georgia Xiromerisiou,Ruey-Meei Wu,Zbigniew K. Wszolek,Karin Wirdefeldt,Linda R. White,Carles Vilariño Güell,Demetrios K. Vassilatis,Enza Maria Valente,Ryan J. Uitti,Hiroyuki Tomiyama,Vera Tadic,Leonidas Stefanis,Young H. Sohn,Peter A. Silburn,Manu Sharma,Aldo Quattrone,Simona Petrucci,Sung Sup Park,Grzegorz Opala,Eugénie Mutez,George D. Mellick,Timothy Lynch,Marie-Anne Loriot,Katja Lohmann,Chin-Hsien Lin,Elli Kyratzi,Rejko Krüger,Christine Klein,Yun Joong Kim,Beom S. Jeon,Barbara Jasinska Myga,John P. A. Ioannidis,Nobutaka Hattori,Georgios M. Hadjigeorgiou,Suzana Gispert,Brian K. Fiske,Alessandro Ferraris,Carlo Ferrarese,Alain Destée,Efthimios Dardiotis,Marie Christine Chartier Harlin,Laura Brighina,Maria Bozi,Magdalena Boczarska Jedynak,Justin A. Bacon,Georg Auburger,Grazia Annesi,Jan O. Aasly,Daniel J. Serie,Alexandra I. Ortolaza +54 more
TL;DR: The results indicate that the association of LRRK2 p.R1398H with Parkinson's disease is independent of SNCA and MAPT variants, and vice versa, in Caucasian and Asian populations.