M
Marie-Laure Welter
Researcher at French Institute of Health and Medical Research
Publications - 84
Citations - 6748
Marie-Laure Welter is an academic researcher from French Institute of Health and Medical Research. The author has contributed to research in topics: Deep brain stimulation & Subthalamic nucleus. The author has an hindex of 35, co-authored 70 publications receiving 5965 citations. Previous affiliations of Marie-Laure Welter include Centre national de la recherche scientifique & Pierre-and-Marie-Curie University.
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Journal ArticleDOI
Subthalamic nucleus stimulation in severe obsessive-compulsive disorder.
Luc Mallet,Mircea Polosan,Nematollah Jaafari,Nicolas Baup,Marie-Laure Welter,Denys Fontaine,Sophie Tezenas du Montcel,Jérôme Yelnik,Isabelle Chereau,Christophe Arbus,Sylvie Raoul,Bruno Aouizerate,Philippe Damier,Stephan Chabardes,Virginie Czernecki,Claire Ardouin,Marie-Odile Krebs,Eric Bardinet,Patrick Chaynes,Pierre Burbaud,Philippe Cornu,Philippe Derost,Thierry Bougerol,Benoit Bataille,Vianney Mattei,Didier Dormont,Bertrand Devaux,Marc Vérin,Jean-Luc Houeto,Pierre Pollak,Alim-Louis Benabid,Yves Agid,Paul Krack,Bruno Millet,Antoine Pelissolo,Non Renseigné +35 more
TL;DR: These preliminary findings suggest that stimulation of the subthalamic nucleus may reduce the symptoms of severe forms of OCD but is associated with a substantial risk of serious adverse events.
Journal ArticleDOI
Stimulation of subterritories of the subthalamic nucleus reveals its role in the integration of the emotional and motor aspects of behavior.
Luc Mallet,Michael Schüpbach,K. N’Diaye,Philippe Remy,Eric Bardinet,Virginie Czernecki,Marie-Laure Welter,Antoine Pelissolo,Merle Ruberg,Yves Agid,Jérôme Yelnik +10 more
TL;DR: Two parkinsonian patients who experienced transient hypomanic states when the subthalamic nucleus (STN) was stimulated during postoperative adjustment of the electrical parameters for antiparkinsonian therapy agreed to have the mood disorder reproduced, in conjunction with motor, cognitive, and behavioral evaluations and concomitant functional neuroimaging.
Journal ArticleDOI
Stimulation of the subthalamic nucleus in Parkinson’s disease: a 5 year follow up
W. M. M. Schüpbach,N. Chastan,Marie-Laure Welter,Jean-Luc Houeto,Valérie Mesnage,A. M. Bonnet,Virginie Czernecki,David Maltête,Andreas Hartmann,Luc Mallet,Bernard Pidoux,Didier Dormont,Soledad Navarro,Philippe Cornu,Alain Mallet,Yves Agid +15 more
TL;DR: Despite moderate motor and cognitive decline, probably due to disease progression, the marked improvement in motor function observed postoperatively was sustained 5 years after neurosurgery.
Journal ArticleDOI
Long-term results of a multicenter study on subthalamic and pallidal stimulation in Parkinson's disease.
Elena Moro,Andres M. Lozano,Pierre Pollak,Yves Agid,Stig Rehncrona,Jens Volkmann,Jaime Kulisevsky,Jose A. Obeso,Alberto Albanese,Marwan Hariz,Marwan Hariz,Niall Quinn,Jans D. Speelman,A.L. Benabid,Valérie Fraix,Alexandre Mendes,Marie-Laure Welter,Jean-Luc Houeto,Philippe Cornu,Didier Dormont,Anna Lena Törnqvist,Ron Ekberg,Alfons Schnitzler,Lars Timmermann,Lars Wojtecki,Andres Gironell,Maria C. Rodriguez-Oroz,Jorge Guridi,Anna Rita Bentivoglio,Maria Fiorella Contarino,Luigi Romito,Massimo Scerrati,Massimo Scerrati,Marc Janssens,Anthony E. Lang +34 more
TL;DR: The 5 to 6 year follow‐up of a multicenter study of bilateral subthalamic nucleus and globus pallidus internus deep brain stimulation in advanced Parkinson's disease patients confirms the long‐term efficacy of STN and GPi DBS in advanced PD.
Journal ArticleDOI
Clinical predictive factors of subthalamic stimulation in Parkinson's disease.
Marie-Laure Welter,J.-L. Houeto,S. Tezenas du Montcel,Valérie Mesnage,A. M. Bonnet,Bernard Pillon,Isabelle Arnulf,Bernard Pidoux,Didier Dormont,Philippe Cornu,Yves Agid +10 more
TL;DR: The results are consistent with the classical inclusion criteria for STN stimulation, but imply that the decision to operate on the oldest patients and/or patients with gait and postural disorders, who are poorly responsive to levodopa, should be weighed carefully.