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Alisa M. Goldstein
Researcher at National Institutes of Health
Publications - 309
Citations - 24663
Alisa M. Goldstein is an academic researcher from National Institutes of Health. The author has contributed to research in topics: Cancer & Population. The author has an hindex of 72, co-authored 297 publications receiving 22773 citations. Previous affiliations of Alisa M. Goldstein include United States Department of Health and Human Services.
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Journal ArticleDOI
Erratum: Genome-wide association analyses of esophageal squamous cell carcinoma in Chinese identify multiple susceptibility loci and gene-environment interactions (Nature Genetics (2012) 44 (1090-1097))
Chen Wu,Peter Kraft,Kan Zhai,Jiang Chang,Zhaoming Wang,Yun Li,Zhibin Hu,Zhonghu He,Wei Hua Jia,Christian C. Abnet,Liming Liang,Nan Hu,Xiaoping Miao,Yifeng Zhou,Zhihua Liu,Qimin Zhan,Yu Liu,Yan Qiao,Yuling Zhou,Guangfu Jin,Chuanhai Guo,Changdong Lu,Haijun Yang,Jianhua Fu,Dianke Yu,Neal D. Freedman,Ti Ding,Wen Tan,Alisa M. Goldstein,Tangchun Wu,Hongbing Shen,Yang Ke,Yi Xin Zeng,Stephen J. Chanock,Philip R. Taylor,Dongxin Lin +35 more
TL;DR: The authors find that there is now no evidence to support the association with esophageal squamous cell carcinoma susceptibility of rs17761864 at 17p13, rs6503659 at 17q21 or rs2847281 at 18p11 in the original data.
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Linkage analysis of anti-CCP levels as dichotomized and quantitative traits using GAW15 single-nucleotide polymorphism scan of NARAC families.
TL;DR: The data suggested that linkage analyses of anti-CCP levels may facilitate identification of rheumatoid arthritis genes but quantitative analyses did not further improve power, and highlighted that quantitative trait linkage results are highly sensitive to phenotype transformation and analytic approaches.
Journal ArticleDOI
Inflated expectations: Rare-variant association analysis using public controls
Jung Kim,Danielle M. Karyadi,Stephen W. Hartley,Bin Zhu,Mingyi Wang,Dongjing Wu,Lei Song,Gregory T. Armstrong,Smita Bhatia,Leslie L. Robison,Yutaka Yasui,Brian D. Carter,Joshua N. Sampson,Neal D. Freedman,Alisa M. Goldstein,Lisa Mirabello,Stephen J. Chanock,Lindsay M. Morton,Sharon A. Savage,G. R. Stewart +19 more
TL;DR: In this paper , the authors leveraged both public controls, gnomAD v2.1 and several datasets sequenced in their laboratory to systematically investigate factors that could contribute to the false-positive discovery, as measured by λΔ95, a measure to quantify the degree of inflation in statistical significance.
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Gene expression profiling identifies two chordoma subtypes associated with distinct molecular mechanisms and clinical outcomes.
Jiwei Bai,Jian Rong Shi,Yazhuo Zhang,Chunzhong Li,Yujia Xiong,Hela Koka,Difei Wang,Tongwu Zhang,Lei Song,Wen Luo,Bin Zhu,Belynda Hicks,Amy Hutchinson,Erin L. Kirk,Melissa A. Troester,Ming-Xiong Li,Yutao Shen,T. Moa,Junmei Wang,Xing Liu,Shuai Wang,Songbai Gui,Mary L. McMaster,Stephen J. Chanock,Dilys M. Parry,Alisa M. Goldstein,Xiaohong R. Yang +26 more
TL;DR: The findings of this study may improve the understanding of subtype-specific tumorigenesis of chordoma and inform clinical prognostication and targeted options.