A
Alisa M. Goldstein
Researcher at National Institutes of Health
Publications - 309
Citations - 24663
Alisa M. Goldstein is an academic researcher from National Institutes of Health. The author has contributed to research in topics: Cancer & Population. The author has an hindex of 72, co-authored 297 publications receiving 22773 citations. Previous affiliations of Alisa M. Goldstein include United States Department of Health and Human Services.
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Journal Article
Familial and sporadic cases of nasopharyngeal carcinoma in Taiwan.
A Ung,Chien-Jen Chen,Paul H. Levine,Yu-Juen Cheng,Louise A. Brinton,I H Chen,Alisa M. Goldstein,Mow-Ming Hsu,S K Chhabra,J Y Chen,Raymond J. Apple,C S Yang,Allan Hildesheim +12 more
TL;DR: The results provide little evidence that a familial form of NPC exists with characteristics notably distinct from sporadic cases, and genetic factors are likely to play an important role in NPC pathogenesis.
Journal ArticleDOI
Mutational signatures in esophageal squamous cell carcinoma from eight countries with varying incidence.
Sarah Moody,Sergey Senkin,S M Ashiqul Islam,S M Ashiqul Islam,Jingwei Wang,Dariush Nasrollahzadeh,Dariush Nasrollahzadeh,Ricardo Cortez Cardoso Penha,Stephen Fitzgerald,Erik N Bergstrom,Erik N Bergstrom,Joshua R. Atkins,Yudou He,Yudou He,Azhar Khandekar,Azhar Khandekar,Karl Smith-Byrne,Christine Carreira,Valerie Gaborieau,Calli Latimer,Emily Thomas,Irina I. Abnizova,Pauline E Bucciarelli,David T. Jones,Jon W. Teague,Behnoush Abedi-Ardekani,Stefano Serra,Jean-Yves Scoazec,Hiva Saffar,Farid Azmoudeh-Ardalan,Masoud Sotoudeh,Arash Nikmanesh,Hossein Poustchi,Ahmadreza Niavarani,Samad Gharavi,Michael Eden,Paul Richman,Lia S Campos,Rebecca C. Fitzgerald,Luis Felipe Ribeiro,Sheila Coelho Soares-Lima,Charles Dzamalala,Blandina T. Mmbaga,Tatsuhiro Shibata,Diana Menya,Alisa M. Goldstein,Nan Hu,Reza Malekzadeh,Abdolreza Fazel,Valerie McCormack,James McKay,Sandra Perdomo,Ghislaine Scelo,Ghislaine Scelo,Estelle Chanudet,Laura Humphreys,Ludmil B Alexandrov,Ludmil B Alexandrov,Paul Brennan,Michael R. Stratton +59 more
TL;DR: In this article, the authors combine the fields of mutational signature analysis with cancer epidemiology to study 552 esophageal squamous cell carcinoma (ESCC) genomes from eight countries with varying incidence rates.
Journal Article
Two-locus linkage analysis of cutaneous malignant melanoma/dysplastic nevi.
TL;DR: Only the 9p locus consistently showed significant evidence for linkage to CMM alone, suggesting that the application of 2L models may be useful to help unravel the complexities of familial melanoma.
Journal ArticleDOI
Assessing the Incremental Contribution of Common Genomic Variants to Melanoma Risk Prediction in Two Population-Based Studies
Anne E. Cust,Martin Drummond,Peter A. Kanetsky,Australian Melanoma Family Study Investigators,Leeds Case-Control Study Investigators,Alisa M. Goldstein,Jennifer H. Barrett,Stuart MacGregor,Matthew Law,Mark M. Iles,Minh Bui,John L. Hopper,Myriam Brossard,Florence Demenais,John C. Taylor,Clive J. Hoggart,Kevin M. Brown,Maria Teresa Landi,Julia Newton-Bishop,Graham J. Mann,D. Timothy Bishop +20 more
TL;DR: Gene variants in the pigmentation pathway, particularly MC1R, were responsible for most of the incremental improvement, and testing of genomic variants can identify people who are susceptible to melanoma despite not having a traditional phenotypic risk profile.
Journal ArticleDOI
High frequency allelic loss on chromosome 17p13.3-p11.1 in esophageal squamous cell carcinomas from a high incidence area in northern China.
Jing Huang,Nan Hu,Alisa M. Goldstein,Michael R. Emmert-Buck,Ze-Zhong Tang,Mark J. Roth,Quan-Hong Wang,Sanford M. Dawsey,Xiao-You Han,Ti Ding,Guang Li,Carol Giffen,Philip R. Taylor +12 more
TL;DR: The search region for major new tumor suppressor genes that may play a role in the pathogenesis of ESCC is narrowed to include the entire short arm of chromosome 17 in 56 ESCC patients from a high risk population in northern China.