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Alisa M. Goldstein
Researcher at National Institutes of Health
Publications - 309
Citations - 24663
Alisa M. Goldstein is an academic researcher from National Institutes of Health. The author has contributed to research in topics: Cancer & Population. The author has an hindex of 72, co-authored 297 publications receiving 22773 citations. Previous affiliations of Alisa M. Goldstein include United States Department of Health and Human Services.
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Journal ArticleDOI
High frequency of CDKN2A alterations in esophageal squamous cell carcinoma from a high-risk Chinese population.
Nan Hu,Chaoyu Wang,Hua Su,Wen-Jun Li,Michael R. Emmert-Buck,Guang Li,Mark J. Roth,Ze-Zhong Tang,Ning Lu,Carol Giffen,Paul S. Albert,Philip R. Taylor,Alisa M. Goldstein +12 more
TL;DR: Both mutation and intragenic allelic loss in CDKN2A appear to play a role in the development of ESCC.
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Overexpression of CDC25B and LAMC2 mRNA and protein in esophageal squamous cell carcinomas and premalignant lesions in subjects from a high-risk population in China.
Jianzhong Shou,Nan Hu,Mikiko Takikita,Mark J. Roth,Laura Lee Johnson,Carol Giffen,Quan-Hong Wang,Chaoyu Wang,Yuan Wang,Hua Su,Li-Hui Kong,Michael R. Emmert-Buck,Alisa M. Goldstein,Stephen M. Hewitt,Philip R. Taylor +14 more
TL;DR: The strong relation of LAMC2 pattern of protein expression to survival suggests a role in prognosis, whereas the association of CDC25B with morphologic progression indicates a potential role as an early detection marker.
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Heterogeneity of risk for melanoma and pancreatic and digestive malignancies: a melanoma case-control study.
Joni L. Rutter,Christina M. Bromley,Alisa M. Goldstein,David E. Elder,Elizabeth A. Holly,DuPont Guerry,Patricia Hartge,Jeffery P. Struewing,David W. Hogg,David W. Hogg,Allan C. Halpern,Richard W. Sagebiel,Margaret A. Tucker +12 more
TL;DR: The authors assessed melanoma risk according to family history of melanoma and other melanoma‐associated malignancies and evaluated the familial heterogeneity of melanomas, pancreaticmalignancies, and gastrointestinal malignancy.
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Influence of Genetic Background and Tissue Types on Global DNA Methylation Patterns
Howard H. Yang,Nan Hu,Chaoyu Wang,Ti Ding,Barbara Dunn,Alisa M. Goldstein,Philip R. Taylor,Maxwell P. Lee +7 more
TL;DR: It was demonstrated that blood and esophageal tissues shared similar DNA methylation patterns within the same individual, suggesting an influence of genetic background onDNA methylation.
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Retrospective family study of childhood medulloblastoma.
David Ng,Theodora Stavrou,Theodora Stavrou,Ling Liu,Michael D. Taylor,Bert Gold,Michael Dean,Michael J. Kelley,Elizabeth C. Dubovsky,Gilbert Vezina,H S Nicholson,Julianne Byrne,James T. Rutka,David W. Hogg,Gregory H. Reaman,Alisa M. Goldstein +15 more
TL;DR: It is concluded that clinically recognizable syndromes are uncommon among patients with medulloblastoma, however, PTCH1 and SUFU mutations are present at a low but significant frequency.