A
Alisa M. Goldstein
Researcher at National Institutes of Health
Publications - 309
Citations - 24663
Alisa M. Goldstein is an academic researcher from National Institutes of Health. The author has contributed to research in topics: Cancer & Population. The author has an hindex of 72, co-authored 297 publications receiving 22773 citations. Previous affiliations of Alisa M. Goldstein include United States Department of Health and Human Services.
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Journal Article
Frequent Inactivation of the TP53 Gene in Esophageal Squamous Cell Carcinoma from a High-Risk Population in China
Nan Hu,Jing Huang,Michael R. Emmert-Buck,Ze-Zhong Tang,Mark J. Roth,Chaoyu Wang,Sanford M. Dawsey,Guang Li,Wen-Jun Li,Quan-Hong Wang,Xiao-You Han,Ti Ding,Carol Giffen,Alisa M. Goldstein,Philip R. Taylor +14 more
TL;DR: The multiple genetic alterations of TP53 in this population at high risk of ESCC indicate that there is a very high degree of genetic instability in these tumors, that TP53 is a primary target for inactivation, and that this tumor suppressor gene plays a critical role in the carcinogenesis process for ESCC.
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Rising melanoma incidence rates of the trunk among younger women in the United States.
TL;DR: The combination of high net drift and low longitudinal age trend show that melanomas are rising preferentially on the trunk among young women, possibly due to increasing UV radiation to previously protected body sites.
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A Single Genetic Origin for the G101W CDKN2A Mutation in 20 Melanoma-Prone Families
Paola Ciotti,Jeffery P. Struewing,Michela Mantelli,Agnès Chompret,Marie-Françoise Avril,Pier Luigi Santi,Margaret A. Tucker,Giovanna Bianchi-Scarrà,Brigitte Bressac-de Paillerets,Alisa M. Goldstein +9 more
TL;DR: The findings showed no significant evidence for mutational heterogeneity, suggesting that all studied families derived from a single ancestral haplotype on which the mutation arose, particularly in southwestern Europe.
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Association of germline mutations in the fumarate hydratase gene and uterine fibroids in women with hereditary leiomyomatosis and renal cell cancer.
Laveta Stewart,Gladys Glenn,Pamela Stratton,Alisa M. Goldstein,Maria J. Merino,Margaret A. Tucker,W. Marston Linehan,Jorge R. Toro +7 more
TL;DR: This study provides the first evidence (to the authors' knowledge) that women with germline mutations in FH and with clinical HLRCC have an increased risk of developing uterine fibroids.
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Index-based dietary patterns and risk of incident hepatocellular carcinoma and mortality from chronic liver disease in a prospective study.
Wen-Qing Li,Wen-Qing Li,Yikyung Park,Katherine A. McGlynn,Albert R. Hollenbeck,Philip R. Taylor,Alisa M. Goldstein,Neal D. Freedman +7 more
TL;DR: Adhering to dietary recommendations may reduce the risk of developing HCC and dying of CLD and the association of two dietary indices, the Healthy Eating Index‐2010 (HEI‐2010) and the alternate Mediterranean Diet Score (aMED), with HCC incidence and CLD mortality in a large U.S. prospective cohort is evaluated.