A
Alisa M. Goldstein
Researcher at National Institutes of Health
Publications - 309
Citations - 24663
Alisa M. Goldstein is an academic researcher from National Institutes of Health. The author has contributed to research in topics: Cancer & Population. The author has an hindex of 72, co-authored 297 publications receiving 22773 citations. Previous affiliations of Alisa M. Goldstein include United States Department of Health and Human Services.
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Journal ArticleDOI
Localization of the gene for Cowden disease to chromosome 10q22-23
Marcel R. Nelen,George W. Padberg,E. A. J. Peeters,Albert Y. Lin,B. Van Den Helm,Rune R. Frants,Valérie Coulon,Alisa M. Goldstein,M.M.M. van Reen,Douglas F. Easton,Rosalind A. Eeles,Shirley Hodgson,John J. Mulvihill,Victoria Murday,Monica Tucker,E.C.M. Mariman,T. M. Starink,Bruce Ponder,Hans-Hilger Ropers,Hannie Kremer,Michel Longy,Charis Eng,Charis Eng +22 more
TL;DR: Cowden disease (CD) (MIM 158350), or multiple hamartoma syndrome, is a rare autosomal dominant familial cancer syndrome with a high risk of breast cancer and central nervous system manifestations of CD were emphasized only recently.
Journal ArticleDOI
Increased risk of pancreatic cancer in melanoma-prone kindreds with p16INK4 mutations.
Alisa M. Goldstein,Mary C. Fraser,Jeffery P. Struewing,Christopher J. Hussussian,Koustubh Ranade,Deborah P. Zametkin,Laura Fontaine,Sara M. Organic,Nicholas C. Dracopoli,Wallace H. Clark,Margaret A. Tucker +10 more
TL;DR: The development of pancreatic cancer in kindreds prone to melanoma may require a p16M mutation, and genetic factors, such as the kind of mutation found in p16INK4, may explain the inconsistent occurrence of other cancers in these kindreds.
Journal ArticleDOI
A Genome-wide Association Study of Lung Cancer Identifies a Region of Chromosome 5p15 Associated with Risk for Adenocarcinoma.
Maria Teresa Landi,Nilanjan Chatterjee,Kai Yu,Lynn R. Goldin,Alisa M. Goldstein,Melissa Rotunno,Lisa Mirabello,Kevin B. Jacobs,William Wheeler,Meredith Yeager,Andrew W. Bergen,Qizhai Li,Qizhai Li,Dario Consonni,Angela Cecilia Pesatori,Sholom Wacholder,Michael J. Thun,Ryan Diver,Martin M. Oken,Jarmo Virtamo,Demetrius Albanes,Zhaoming Wang,Laurie Burdette,Kimberly F. Doheny,Elizabeth W. Pugh,Cathy C. Laurie,Paul Brennan,Rayjean J. Hung,Valerie Gaborieau,James McKay,Mark Lathrop,John R. McLaughlin,Ying Wang,Ming-Sound Tsao,Margaret R. Spitz,Yufei Wang,Hans E. Krokan,Lars J. Vatten,Frank Skorpen,Egil Arnesen,Simone Benhamou,Christine Bouchard,Andres Metsapalu,Tõnu Vooder,Mari Nelis,Kristian Välk,John K. Field,Chu Chen,Gary E. Goodman,Patrick Sulem,Gudmar Thorleifsson,Thorunn Rafnar,Timothy Eisen,Wiebke Sauter,Albert Rosenberger,Heike Bickeböller,Angela Risch,Jenny Chang-Claude,H.-Erich Wichmann,Kari Stefansson,Richard S. Houlston,Christopher I. Amos,Joseph F. Fraumeni,Sharon A. Savage,Pier Alberto Bertazzi,Margaret A. Tucker,Stephen J. Chanock,Neil E. Caporaso +67 more
TL;DR: A lung cancer GWAS identified a distinct hereditary contribution to adenocarcinoma, and previously reported association signals on 15q25 and 6p21 were refined, but no additional loci reached genome-wide significance.
Journal ArticleDOI
Detectable clonal mosaicism and its relationship to aging and cancer
Kevin B. Jacobs,Kevin B. Jacobs,Meredith Yeager,Meredith Yeager,Weiyin Zhou,Weiyin Zhou,Sholom Wacholder,Zhaoming Wang,Zhaoming Wang,Benjamín Rodríguez-Santiago,Amy Hutchinson,Amy Hutchinson,Xiang Deng,Xiang Deng,Chenwei Liu,Chenwei Liu,Marie Josephe Horner,Michael Cullen,Michael Cullen,Caroline G. Epstein,Laurie Burdett,Laurie Burdett,Michael Dean,Nilanjan Chatterjee,Joshua N. Sampson,Charles C. Chung,Joseph Kovaks,Susan M. Gapstur,Victoria L. Stevens,Lauren T. Teras,Mia M. Gaudet,Demetrius Albanes,Stephanie J. Weinstein,Jarmo Virtamo,Philip R. Taylor,Neal D. Freedman,Christian C. Abnet,Alisa M. Goldstein,Nan Hu,Kai Yu,Jian-Min Yuan,Jian-Min Yuan,Linda M. Liao,Ti Ding,You-Lin Qiao,Yu Tang Gao,Woon-Puay Koh,Yong-Bing Xiang,Ze Zhong Tang,Jin-Hu Fan,Melinda C. Aldrich,Christopher I. Amos,William J. Blot,Cathryn H. Bock,Elizabeth M. Gillanders,Curtis C. Harris,Christopher A. Haiman,Brian E. Henderson,Laurence N. Kolonel,Loic Le Marchand,Lorna H. McNeill,Benjamin A. Rybicki,Ann G. Schwartz,Lisa B. Signorello,Margaret R. Spitz,John K. Wiencke,Margaret Wrensch,Xifeng Wu,Krista A. Zanetti,Regina G. Ziegler,Jonine D. Figueroa,Montserrat Garcia-Closas,Núria Malats,Gaëlle Marenne,Ludmila Prokunina-Olsson,Dalsu Baris,Molly Schwenn,Alison Johnson,Maria Teresa Landi,Lynn R. Goldin,Dario Consonni,Pier Alberto Bertazzi,Melissa Rotunno,Preetha Rajaraman,Ulrika Andersson,Laura E. Beane Freeman,Christine D. Berg,Julie E. Buring,Mary Ann Butler,Tania Carreón,Maria Feychting,Anders Ahlbom,J. Michael Gaziano,Graham G. Giles,Graham G. Giles,Göran Hallmans,Susan E. Hankinson,Patricia Hartge,Roger Henriksson,Roger Henriksson,Peter D. Inskip,Christoffer Johansen,Annelie Landgren,Roberta McKean-Cowdin,Dominique S. Michaud,Dominique S. Michaud,Beatrice Melin,Ulrike Peters,Ulrike Peters,Avima M. Ruder,Howard D. Sesso,Gianluca Severi,Gianluca Severi,Xiao-Ou Shu,Kala Visvanathan,Emily White,Emily White,Alicja Wolk,Anne Zeleniuch-Jacquotte,Wei Zheng,Debra T. Silverman,Manolis Kogevinas,Juan R. González,Olaya Villa,Donghui Li,Eric J. Duell,Harvey A. Risch,Sara H. Olson,Charles Kooperberg,Brian M. Wolpin,Li Jiao,Manal M. Hassan,William Wheeler,Alan A. Arslan,H. Bas Bueno-de-Mesquita,Charles S. Fuchs,Steven Gallinger,Myron D. Gross,Elizabeth A. Holly,Alison P. Klein,Andrea Z. LaCroix,Margaret T. Mandelson,Margaret T. Mandelson,Gloria M. Petersen,Marie-Christine Boutron-Ruault,Paige M. Bracci,Federico Canzian,Kenneth J. Chang,Michelle Cotterchio,Edward Giovannucci,Michael Goggins,Judith A. Hoffman Bolton,Mazda Jenab,Kay-Tee Khaw,Vittorio Krogh,Robert C. Kurtz,Robert R. McWilliams,Julie B. Mendelsohn,Kari G. Rabe,Elio Riboli,Anne Tjønneland,Geoffrey S. Tobias,Dimitrios Trichopoulos,Dimitrios Trichopoulos,Joanne W. Elena,Herbert Yu,Laufey T. Amundadottir,Rachael Z. Stolzenberg-Solomon,Peter Kraft,Fredrick R. Schumacher,Daniel O. Stram,Sharon A. Savage,Lisa Mirabello,Irene L. Andrulis,Jay S. Wunder,Ana Patino Garcia,Luis Sierrasesà maga,Donald A. Barkauskas,Richard Gorlick,Mark P. Purdue,Wong Ho Chow,Lee E. Moore,Kendra Schwartz,Faith G. Davis,Ann W. Hsing,Sonja I. Berndt,Amanda Black,Nicolas Wentzensen,Louise A. Brinton,Jolanta Lissowska,Beata Peplonska,Katherine A. McGlynn,Michael B. Cook,Barry I. Graubard,Christian P. Kratz,Christian P. Kratz,Mark H. Greene,Ralph L. Erickson,David J. Hunter,Gilles Thomas,Robert N. Hoover,Francisco X. Real,Francisco X. Real,Joseph F. Fraumeni,Neil E. Caporaso,Margaret A. Tucker,Nathaniel Rothman,Luis A. Pérez-Jurado,Stephen J. Chanock +208 more
TL;DR: In an analysis of 31,717 cancer cases and 26,136 cancer-free controls from 13 genome-wide association studies, this paper observed large chromosomal abnormalities in a subset of clones in DNA obtained from blood or buccal samples.
Journal ArticleDOI
A shared susceptibility locus in PLCE1 at 10q23 for gastric adenocarcinoma and esophageal squamous cell carcinoma
Christian C. Abnet,Neal D. Freedman,Nan Hu,Zhaoming Wang,Zhaoming Wang,Kai Yu,Xiao-Ou Shu,Jian-Min Yuan,Wei Zheng,Sanford M. Dawsey,Linda M. Dong,Maxwell P. Lee,Ti Ding,You-Lin Qiao,Yu-Tang Gao,Woon-Puay Koh,Yong-Bing Xiang,Ze Zhong Tang,Jin-Hu Fan,Chaoyu Wang,William Wheeler,Mitchell H. Gail,Meredith Yeager,Meredith Yeager,Jeff Yuenger,Jeff Yuenger,Amy Hutchinson,Amy Hutchinson,Kevin B. Jacobs,Kevin B. Jacobs,Carol Giffen,Laurie Burdett,Laurie Burdett,Joseph F. Fraumeni,Margaret A. Tucker,Wong Ho Chow,Alisa M. Goldstein,Stephen J. Chanock,Philip R. Taylor +38 more
TL;DR: A genome-wide association study of gastric cancer and esophageal squamous cell carcinoma in ethnic Chinese subjects in which 551,152 SNPs were genotyped could provide insight into the high incidence of both cancers in China.