Alisa M. Goldstein

TL;DR: This large population‐based study not only supports the role of gallstones in biliary carcinogenesis but also suggests that the underlying genetic or lifestyle determinants of stones within families contribute to the risk of biliary tract cancer.

TL;DR: The very high frequency LOH regions identified here may point to major susceptibility genes, including potential tumor suppressor genes and inherited gene loci, which will assist in understanding the molecular events involved in esophageal carcinogenesis and may help in the development of markers for genetic susceptibility testing and screening for the early detection of this cancer.

TL;DR: The number of loci identified using EVRNVR suggests that a threshold‐based phenotype may better identify loci affecting smoking history, and some of these regions may represent loci increasing vulnerability to both smoking and alcoholism.

TL;DR: In this paper, the authors identify genetic variants that affect risk for gastric cancer, and perform whole-exome sequence analysis to identify mutations in genes that regulate homologous DNA recombination.

TL;DR: It was showed that Hp is the dominant member of the non-malignant gastric tissue microbiota in many gastric cancer patients, and taxonomic and derived functional profiles of gastric microbiota were distinct from those found in other body sites and had higher inter-subject dissimilarity.