Ana T. Duggan

TL;DR: By using sequence deamination patterns and fragment length distributions, schmutzi accurately reconstructs the endogenous mitochondrial genome sequence even when contamination exceeds 50 %, and given sufficient coverage, schMutzi also produces reliable estimates of contamination across a range of contamination rates.

TL;DR: Molecular-clock analyses revealed a strong clock-like structure and that the timescale of smallpox evolution is more recent than often supposed, with the diversification of major viral lineages only occurring within the 18th and 19th centuries, concomitant with the development of modern vaccination.

TL;DR: This work performed hybridization capture using baits designed from the mitochondrial (mtDNA) genomes of Plasmodium spp.

TL;DR: It is demonstrated that HBV evolution is characterized by a marked lack of temporal structure, which confounds attempts to use molecular clock-based methods to date the origin of this virus over the time-frame sampled so far, and means that phylogenetic measures alone cannot yet be used to determine HBV sequence authenticity.

TL;DR: In this paper, the authors report that North American deer mice (Peromyscus maniculatus) are susceptible to SARS-CoV-2 infection following intranasal exposure to a human isolate, resulting in viral replication in the upper and lower respiratory tract with little or no signs of disease.