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Annika Scheynius
Researcher at Karolinska Institutet
Publications - 218
Citations - 16576
Annika Scheynius is an academic researcher from Karolinska Institutet. The author has contributed to research in topics: Malassezia sympodialis & Immunoglobulin E. The author has an hindex of 62, co-authored 215 publications receiving 15284 citations. Previous affiliations of Annika Scheynius include Karolinska University Hospital & Boston Children's Hospital.
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Journal ArticleDOI
Exosomes with Immune Modulatory Features Are Present in Human Breast Milk
Charlotte Admyre,Sara M. Johansson,Khaleda Rahman Qazi,Jan-Jonas Filén,Riitta Lahesmaa,Mikael Norman,Etienne P. A. Neve,Annika Scheynius,Susanne Gabrielsson +8 more
TL;DR: Functional analysis revealed that the vesicle preparation inhibited anti-CD3-induced IL-2 and IFN-γ production from allogeneic and autologous PBMC incubated with milk vesicles, concluding that human breast milk contains exosomes with the capacity to influence immune responses.
Journal ArticleDOI
Differential DNA Methylation in Purified Human Blood Cells: Implications for Cell Lineage and Studies on Disease Susceptibility
Lovisa E. Reinius,Nathalie Acevedo,Maaike Joerink,Göran Pershagen,Sven-Erik Dahlén,Dario Greco,Cilla Söderhäll,Annika Scheynius,Juha Kere,Juha Kere,Juha Kere +10 more
TL;DR: In healthy male blood donors there is important variation in the methylation profiles of whole blood, mononuclear cells, granulocytes, and cells from seven selected purified lineages, indicating that whole blood methylation results might be unintelligible.
Journal ArticleDOI
Epigenome-wide association data implicate DNA methylation as an intermediary of genetic risk in rheumatoid arthritis
Yun Liu,Martin J. Aryee,Leonid Padyukov,M. Daniele Fallin,M. Daniele Fallin,Espen Hesselberg,Arni Runarsson,Lovisa E. Reinius,Nathalie Acevedo,Margaret A. Taub,Margaret A. Taub,Marcus Ronninger,Klementy Shchetynsky,Annika Scheynius,Juha Kere,Lars Alfredsson,Lars Klareskog,Tomas J. Ekström,Andrew P. Feinberg,Andrew P. Feinberg +19 more
TL;DR: DNA methylation is a potential mediator of genetic risk for rheumatoid arthritis and is corrected for cellular heterogeneity by estimating and adjusting for cell-type proportions in blood-derived DNA samples and used mediation analysis to filter out associations likely to be a consequence of disease.
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Diagnosis and treatment of atopic dermatitis in children and adults: European Academy of Allergology and Clinical Immunology/American Academy of Allergy, Asthma and Immunology/PRACTALL Consensus Report
Cezmi A. Akdis,M. Akdis,T. Bieber,Carsten Bindslev-Jensen,Mark Boguniewicz,Philippe Eigenmann,Qutayba Hamid,Alexander Kapp,Donald Y.M. Leung,J Lipozencic,Thomas A. Luger,Antonella Muraro,Natalija Novak,Thomas A.E. Platts-Mills,Lanny J. Rosenwasser,Annika Scheynius,F. E. R. Simons,Jonathan M. Spergel,K Turjanmaa,Ulrich Wahn,S Weidinger,Thomas Werfel,Torsten Zuberbier +22 more
TL;DR: The consensus report is endorsed by both academies and aims to serve as a guideline for clinical practice in Europe as well as in North America.
Journal ArticleDOI
MicroRNAs: novel regulators involved in the pathogenesis of psoriasis?
Enikö Sonkoly,Tianling Wei,Peter Janson,Annika Sääf,Lena Lundeberg,Maria Tengvall-Linder,Gunnar Norstedt,Harri Alenius,Bernhard Homey,Annika Scheynius,Mona Ståhle,Andor Pivarcsi +11 more
TL;DR: It is shown for the first time that psoriasis-affected skin has a specific microRNA expression profile when compared with healthy human skin or with another chronic inflammatory skin disease, atopic eczema.