A
Anthony Ogwu
Researcher at Harvard University
Publications - 29
Citations - 2124
Anthony Ogwu is an academic researcher from Harvard University. The author has contributed to research in topics: Population & Lopinavir. The author has an hindex of 17, co-authored 29 publications receiving 1961 citations. Previous affiliations of Anthony Ogwu include Beth Israel Deaconess Medical Center.
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Journal ArticleDOI
Antiretroviral Regimens in Pregnancy and Breast-Feeding in Botswana
Roger L. Shapiro,Anthony Ogwu,Douglas Kitch,Shahin Lockman,Claire Moffat,Joseph Makhema,Sikhulile Moyo,Ibou Thior,Kenneth McIntosh,E. van Widenfelt,Jean Leidner,Kathleen M. Powis,Aida Asmelash,Esther Tumbare,S. Zwerski,U. Sharma,E. Handelsman,K. Mburu,Oluwemimo Jayeoba,E. Moko,Sajini Souda,E. Lubega,M. Akhtar,Carolyn Wester,R. Tuomola,W. Snowden,M. Martinez-Tristani,Loeto Mazhani,Myron Essex,Abstr Act +29 more
TL;DR: All regimens of HAART from pregnancy through 6 months post partum resulted in high rates of virologic suppression, with an overall rate of mother-to-child transmission of 1.1%.
Journal ArticleDOI
Adaptation of HIV-1 to human leukocyte antigen class I
Yuka Kawashima,Katja Pfafferott,John Frater,Philippa C Matthews,Rebecca Payne,Marylyn M. Addo,Hiroyuki Gatanaga,Mamoru Fujiwara,Atsuko Hachiya,Hirokazu Koizumi,Nozomi Kuse,Shinichi Oka,Anna Duda,Andrew J. Prendergast,Hayley Crawford,Alasdair Leslie,Zabrina L. Brumme,Chanson J. Brumme,Todd M. Allen,Christian Brander,Christian Brander,Richard A. Kaslow,Jianming Tang,Eric Hunter,Susan Allen,Joseph Mulenga,S. Branch,T. Roach,Mina John,Simon Mallal,Anthony Ogwu,Roger L. Shapiro,Julia G. Prado,Sarah Fidler,Jonathan Weber,Oliver G. Pybus,Paul Klenerman,Thumbi Ndung'u,Rodney E. Phillips,David E. Heckerman,P.R. Harrigan,Bruce D. Walker,Bruce D. Walker,Bruce D. Walker,Masafumi Takiguchi,Philip J. R. Goulder,Philip J. R. Goulder +46 more
TL;DR: This process of viral adaptation may dismantle the well-established HLA associations with control of HIV infection that are linked to the availability of key epitopes, and highlights the challenge for a vaccine to keep pace with the changing immunological landscape presented by HIV.
Journal ArticleDOI
Highly active antiretroviral therapy and adverse birth outcomes among HIV-infected women in Botswana.
Jennifer Y. Chen,Heather J. Ribaudo,Sajini Souda,Natasha Parekh,Anthony Ogwu,Shahin Lockman,Shahin Lockman,Kathleen M. Powis,Scott Dryden-Peterson,Tracy Creek,William Jimbo,Tebogo Madidimalo,Joseph Makhema,Max Essex,Roger L. Shapiro,Roger L. Shapiro +15 more
TL;DR: HAART receipt during pregnancy was associated with increased PTD, SGA, and SB, and low CD4(+) was independently associated with SB and S GA, and maternal hypertension during pregnancy with PTD and SGA.
Journal ArticleDOI
Increased Risk of Preterm Delivery Among HIV-Infected Women Randomized to Protease Versus Nucleoside Reverse Transcriptase Inhibitor-Based HAART During Pregnancy
Kathleen M. Powis,Douglas Kitch,Anthony Ogwu,Michael Hughes,Shahin Lockman,Shahin Lockman,Jean Leidner,Erik van Widenfelt,Claire Moffat,Sikhulile Moyo,Joseph Makhema,Max Essex,Roger L. Shapiro +12 more
TL;DR: PI-based HAART was associated with increased preterm delivery but not increased infant hospitalizations or mortality in a clinical trial setting, and the association between PI use and lower increase in BMI in late pregnancy warrants further study.
Journal ArticleDOI
Effects of in utero antiretroviral exposure on longitudinal growth of HIV-exposed uninfected infants in Botswana.
Kathleen M. Powis,Laura M. Smeaton,Anthony Ogwu,Shahin Lockman,Scott Dryden-Peterson,Erik van Widenfelt,Jean Leidner,Joseph Makhema,Max Essex,Roger L. Shapiro +9 more
TL;DR: Lower weights in HAART-exposed uninfected infants at birth were rapidly corrected during the first 6 months of life, and the incidence of wasting or stunting did not differ between exposure groups.