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Mina John

Researcher at Royal Perth Hospital

Publications -  142
Citations -  11188

Mina John is an academic researcher from Royal Perth Hospital. The author has contributed to research in topics: Human leukocyte antigen & Epitope. The author has an hindex of 38, co-authored 139 publications receiving 10739 citations. Previous affiliations of Mina John include University of Western Australia & Fiona Stanley Hospital.

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Circulating microRNAs in sera correlate with soluble biomarkers of immune activation but do not predict mortality in ART treated individuals with HIV-1 infection : a case control study

Daniel D Murray, +1489 more
- 14 Oct 2015 - 
TL;DR: No associations with mortality were found with any circulating miRNAs studied and these results cast doubt onto the effectiveness of circulating miRNA as early predictors of mortality or the major underlying diseases that contribute to mortality in participants treated for HIV-1 infection.
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The major genetic determinants of HIV-1 control affect HLA class I peptide presentation

Florencia Pereyra, +336 more
- 10 Dec 2010 - 
TL;DR: Differences in binding to viral peptide antigens by HLA may be the major factors underlying genetic differences between HIV controllers and progressors, and genome-wide association results implicate the nature of the HLA–viral peptide interaction as the major factor modulating durable control of HIV infection.
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Evidence of HIV-1 Adaptation to HLA-Restricted Immune Responses at a Population Level

Corey Moore, +6 more
- 24 May 2002 - 
TL;DR: A fundamental role is supported for HLA-restricted immune responses in driving and shaping HIV-1 evolution in vivo and at a population level the degree of HLA–associated selection in viral sequence was predictive of viral load.
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Contribution of nucleoside analogue reverse transcriptase inhibitors to subcutaneous fat wasting in patients with HIV infection.

Simon Mallal, +4 more
- 01 Jul 2000 - 
TL;DR: NRTIs do have an independent contribution to fat wasting, but PI are the predominant influence and may act synergistically with NRTIs, suggesting a non-linear decline in fat over time.
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Adaptation of HIV-1 to human leukocyte antigen class I

Yuka Kawashima, +46 more
- 02 Apr 2009 - 
TL;DR: This process of viral adaptation may dismantle the well-established HLA associations with control of HIV infection that are linked to the availability of key epitopes, and highlights the challenge for a vaccine to keep pace with the changing immunological landscape presented by HIV.