A
Arnold L. Demain
Researcher at Drew University
Publications - 425
Citations - 21576
Arnold L. Demain is an academic researcher from Drew University. The author has contributed to research in topics: Streptomyces clavuligerus & Clostridium thermocellum. The author has an hindex of 66, co-authored 424 publications receiving 20140 citations. Previous affiliations of Arnold L. Demain include Massachusetts Institute of Technology & Merck & Co..
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Journal ArticleDOI
Minimal media for quantitative studies with Bacillus subtilis.
TL;DR: The present paper describes the development of truly minimal media which allow maximal colony formation by spores and vegetative cells of this organism, as determined on nutrient agar.
Journal ArticleDOI
A pure enzyme catalyzing penicillin biosynthesis
TL;DR: Isopenicillin N synthetase (cyclase) has been purified to homogeneity from Cephalosporium acremonium strain C-10 and can be stabilized with sucrose and stored at -20 degrees C for several weeks without any loss in activity.
Journal ArticleDOI
True cellulase production by Clostridium thermocellum grown on different carbon sources
TL;DR: It appears that cellulase is best produced by cells high in ATP and low in Dp and its electrical component DY, and a direct correlation between cellulase production and intracellular ATP levels and an inverse relationship of cellulaseProduction with ΔY and Δp values is noted.
Journal ArticleDOI
Regulation of Cellulase Formation in Clostridium thermocellum
TL;DR: It appears that rapid growth on a soluble sugar such as cellobiose causes carbon source repression which is relieved during slow growth on crystalline cellulose or during the growth lag on fructose or sorbitol, and the reason for the lack of cellulase derepression during the Growth lag on glucose is unexplained.
Book ChapterDOI
Microbial secondary metabolism: a new theoretical frontier for academia, a new opportunity for industry.
TL;DR: The pathways of secondary metabolism provide a new frontier for basic investigations of enzymology, control and differentiation and Great potential exists for the discovery of antiviral, antiparasitic, antitumour and pharmacological compounds and new agricultural products.