A
Arnold L. Demain
Researcher at Drew University
Publications - 425
Citations - 21576
Arnold L. Demain is an academic researcher from Drew University. The author has contributed to research in topics: Streptomyces clavuligerus & Clostridium thermocellum. The author has an hindex of 66, co-authored 424 publications receiving 20140 citations. Previous affiliations of Arnold L. Demain include Massachusetts Institute of Technology & Merck & Co..
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Journal ArticleDOI
Impact of novel microbial secondary metabolites on the pharma industry
Dulce Ramírez-Rendon,Ajit Kumar Passari,Beatriz Ruiz-Villafán,Romina Rodríguez-Sanoja,Sergio Sánchez,Arnold L. Demain +5 more
TL;DR: In this article , a review of the recent developments in the field of metagenomics and genome mining is presented to illustrate the potential that some modern technologies such as genome mining offer for the discovery and development of new molecules, with different functions like therapeutic alternatives needed to overcome current severe problems such as the SARS-CoV-2 pandemic, antibiotic resistance, and other emerging diseases.
Journal ArticleDOI
Regulation of lysine ɛ-aminotransferase by carbon source and lack of control by phosphate in Streptomyces clavuligerus
N. Rius,Arnold L. Demain +1 more
TL;DR: The results thus show that the negative effects of 2% glycerol and 3% starch and 100 mM phosphate on cephalosporin production are not due to an effect on production of LAT activity, however, repression of Lat activity by 3% Glycerol would be expected to play a negative role in antibiotic production.
Book ChapterDOI
Optimization of Fermentation Processes Through the Control of In Vivo Inactivation of Microbial Biosynthetic Enzymes
Journal ArticleDOI
Achievements in microbial technology
TL;DR: The future is thus insured for the expanded use of microorganisms in the biotechnological world and the continued improvement in microbial processes to reduce the cost of drugs, enzymes and specialty chemicals.