Attila Tóth

TL;DR: It is shown that Scc2p forms a complex with a novel protein, Scc4p, which is also necessary for sister cohesion, suggesting that a major role for the SCC2p/SCC4p complex is to facilitate the loading of cohesin complexes onto chromosomes.

TL;DR: This and a previous study have identified six proteins essential for establishing or maintaining sister chromatid cohesion, four of which are subunits of a 'Cohesin' complex that binds chromosomes from late G1 until the onset of anaphase.

TL;DR: The behavior of two previously uncharacterized meiosis-specific mouse HORMA-domain proteins—HORMAD1 and HORMAD2—in wild-type mice and in mutants defective in DSB processing or SC formation are examined, raising the possibility that involvement of meiotic HORMA -domain proteins in the regulation of homologue interactions is conserved in mammals.

TL;DR: It is shown that APCCdc20 allows activation of Cdc14 and promotes exit from mitosis by mediating proteolysis of Pds1 and the S phase cyclin Clb5 in the yeast Saccharomyces cerevisiae.

TL;DR: It is concluded that monopolar attachment during meiosis I requires at least one meiosis-specific protein and is independent of the process that protects sister centromere cohesion.