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Axel Ullrich

Researcher at Max Planck Society

Publications -  436
Citations -  63142

Axel Ullrich is an academic researcher from Max Planck Society. The author has contributed to research in topics: Receptor tyrosine kinase & Tyrosine kinase. The author has an hindex of 124, co-authored 436 publications receiving 61445 citations. Previous affiliations of Axel Ullrich include Institute of Molecular and Cell Biology & Agency for Science, Technology and Research.

Papers
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Journal ArticleDOI

Multisite serine phosphorylation of the insulin and IGF-I receptors in transfected cells.

Tahir S Pillay, +4 more
- 19 Aug 1991 - 
TL;DR: It is concluded that insulin/IGF‐I and PMA stimulate phosphorylated of the same sites, but differ in the extents of phosphorylation.
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Distinct structural specificities for functional coupling of the epidermal growth factor receptor to calcium-signalling versus phospholipase A2 responses.

Nashrudeen Hack, +4 more
- 01 May 1991 - 
TL;DR: A clear distinction is pointed to in the biochemical mechanism and role for receptor autophosphorylation in functional coupling of the EGF receptor to PLA2 activation versus Ca2+ signalling.
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Evidence that two naturally occurring human insulin receptor alpha-subunit variants are immunologically distinct.

Giorgio Sesti, +9 more
- 01 Jan 1992 - 
TL;DR: The data reported herein demonstrate that the two naturally occurring insulin-receptor variants are immunologically distinct and indicate that the HIR-B variant is predominantly expressed in liver compared with other human tissues.
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The receptor-like protein-tyrosine phosphatase DEP-1 is constitutively associated with a 64-kDa protein serine/threonine kinase.

Bahija Jallal, +7 more
- 02 May 1997 - 
TL;DR: The analysis of PTP expression in mammary carcinoma cell lines resulted in the molecular cloning of a receptor-like PTP, also known as DEP-1, which suggests a possible mechanism of DEp-1 regulation in tumor cell lines involving serine/threonine and/or tyrosine phosphorylation.
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Activation of HER3 Interferes with Antitumor Effects of Axl Receptor Tyrosine Kinase Inhibitors: Suggestion of Combination Therapy

Robert Torka, +7 more
- 01 Apr 2014 - 
TL;DR: It is demonstrated that inhibition of Axl by short interfering RNA or the tyrosine kinase inhibitor (TKI) BMS777607 induces the expression of human epidermal growth factor receptor 3 (HER3) and the neuregulin 1(NRG1)-dependent phosphorylation of HER3 in MDA-MB231 and Ovcar8 cells.