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Axel Ullrich

Researcher at Max Planck Society

Publications -  436
Citations -  63142

Axel Ullrich is an academic researcher from Max Planck Society. The author has contributed to research in topics: Receptor tyrosine kinase & Tyrosine kinase. The author has an hindex of 124, co-authored 436 publications receiving 61445 citations. Previous affiliations of Axel Ullrich include Institute of Molecular and Cell Biology & Agency for Science, Technology and Research.

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Association of human protein-tyrosine phosphatase kappa with members of the armadillo family.

TL;DR: It is shown here that hPTPκ expression is dependent on cell density and find it colocalized with two members of the arm family of proteins, β-catenin and γ-catin/plakoglobin, at adherens junctions, and the identification of specific binding partners for this receptor-like PTP provides insight into the mechanisms of its biological action.
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Functional analysis of the ligand binding site of EGF-receptor utilizing chimeric chicken/human receptor molecules.

TL;DR: It is concluded that domain III of the extracellular region of the human receptor, which is flanked by the two cysteine‐rich domains is a major ligand‐binding domain of the EGF‐receptor.
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All autophosphorylation sites of epidermal growth factor (EGF) receptor and HER2/neu are located in their carboxyl-terminal tails. Identification of a novel site in EGF receptor.

TL;DR: All autophosphorylation sites of EGF receptor and HER2/neu are located in their carboxyl-terminal tails, according to mutational analysis and microsequencing techniques used to localize and identify new autoph phosphorylation site(s).
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Receptors for insulin and insulin-like growth factor-I can form hybrid dimers. Characterisation of hybrid receptors in transfected cells

TL;DR: The formation of hybrid insulin/insulin-like growth factor-I(IGF-I) receptors in transfected rodent fibroblasts is demonstrated by examining reactivity with species- and receptor-specific monoclonal antibodies, and responses to these ligands were asymmetrical.
Journal Article

Expression of the hst-1 and c-kit protooncogenes in human testicular germ cell tumors.

TL;DR: A significant association between tumor stage and hst-1 expression in the nonseminoma group was found and an inverse relationship in the expression pattern of these 2 oncogenes in human testicular germ cell tumors was demonstrated.