B
B. Zbar
Researcher at National Institutes of Health
Publications - 6
Citations - 2194
B. Zbar is an academic researcher from National Institutes of Health. The author has contributed to research in topics: Chromosomal translocation & Penetrance. The author has an hindex of 6, co-authored 6 publications receiving 2104 citations. Previous affiliations of B. Zbar include Université de Montréal.
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Journal ArticleDOI
Germline and somatic mutations in the tyrosine kinase domain of the MET proto-oncogene in papillary renal carcinomas
Laura S. Schmidt,Fuh Mei Duh,F. Chen,Takeshi Kishida,Gladys Glenn,Peter L. Choyke,Stephen W. Scherer,Zhengping Zhuang,Irina A. Lubensky,Michael Dean,Rando Allikmets,Abirami Chidambaram,Ulf S.R. Bergerheim,J. T. Feltis,C. Casadevall,A. Zamarron,M. Bernues,Stéphane Richard,C. J. M. Lips,McClellan M. Walther,Lap-Chee Tsui,Laura Geil,Mary Lou Orcutt,Thomas Stackhouse,J. Lipan,L. Slife,Hiltrud Brauch,Jochen Decker,G. Niehans,M. D. Hughson,Holger Moch,Stefan Storkel,Michael I. Lerman,W.M. Linehan,B. Zbar +34 more
TL;DR: The results suggest that missense mutations located in the MET proto-oncogene lead to constitutive activation of the MET protein and papillary renal carcinomas.
Journal ArticleDOI
Loss of alleles of loci on the short arm of chromosome 3 in renal cell carcinoma.
TL;DR: Examining tumours from 18 patients with non-hereditary renal cell carcinomas and found loss of alleles at loci on the short arm of chromosome 3 in all eleven of the patients who could be evaluated, finds clues to identification of new loci of gene loss in common adult solid tumours.
Journal ArticleDOI
Loss of Alleles of Loci on the Short Arm of Chromosome 3 in Renal Cell Carcinoma
TL;DR: In this article, the authors examined tumours from 18 patients with non-hereditary renal cell carcinomas and found loss of alleles at loci on the short arm of chromosome 3 in all eleven of the patients who could be evaluated.
Journal ArticleDOI
Germline and Somatic Mutations in the Tyrosine Kinase Domain of the MET Proto-Oncogene in Papillary Renal Carcinomas
Laura S. Schmidt,Fuh Mei Duh,F. Chen,Takeshi Kishida,Gladys Glenn,Peter L. Choyke,Stephen W. Scherer,Zhengping Zhuang,Irina A. Lubensky,Michael Dean,Rando Allikmets,Abirami Chidambaram,Ulf S.R. Bergerheim,J. T. Feltis,C. Casadevall,A. Zamarron,M. Bernues,Stéphane Richard,C. J. M. Lips,McClellan M. Walther,Lap-Chee Tsui,Laura Geil,Mary Lou Orcutt,Thomas Stackhouse,J. Lipan,L. Slife,Hiltrud Brauch,Jochen Decker,G. Niehans,M. D. Hughson,Holger Moch,Stefan Storkel,Michael I. Lerman,W.M. Linehan,B. Zbar +34 more
TL;DR: This paper found that missense mutations located in the tyrosine kinase domain of the MET gene in the germline of affected members of HPRC families and in a subset of sporadic papillary renal carcinomas.
Journal Article
Loss of heterozygosity in a gene coding for a thyroid-hormone receptor in lung cancers
F Leduc,Hiltrud Brauch,C Hajj,Alexander Dobrovic,F Kaye,A Gazdar,Jw Harbour,Os Pettengill,Gd Sorenson,van den Anke Berg,Klaas Kok,B Campling,François Paquin,Wec Bradley,B. Zbar,John D. Minna,Charles H.C.M. Buys,J. Ayoub +17 more
TL;DR: The ERBA beta gene codes for a DNA-binding thyroid hormone receptor (THR) and maps to chromosome 3p21-p25, overlapping a 3p deletion characterizing small-cell lung carcinoma (SCLC), showing that the3p deletion in SCLC includes this gene.