Handbook of solubility data for pharmaceuticals , Handbook of solubility data for pharmaceuticals , کتابخانه دیجیتال جندی شاپور اهواز

http://chemistry-chemists.com/chemister/Spravochniki/handbook-of-solubility-data-for-pharmaceuticals-2010.pdf

Handbook of Solubility Data for Pharmaceuticals

As a novel class of porous crystalline materials, hydrogen-bonded organic frameworks (HOFs), self-assembled from organic or metal-organic building blocks through intermolecular hydrogen-bonding interactions, have attracted more and more attention. Over the past decade, a number of porous HOFs have been constructed through judicious selection of H-bonding motifs, which are further enforced by other weak intermolecular interactions such as π-π stacking and van der Waals forces and framework interpenetration. Since the H-bonds are weaker than coordinate and covalent bonds used for the construction of metal-organic frameworks (MOFs) and covalent organic frameworks (COFs), HOFs have some unique features such as mild synthesis condition, solution processability, easy healing, and regeneration. These features enable HOFs to be a tunable platform for the construction of functional materials. Here, we review the H-bonding motifs used for constructing porous HOFs and highlight some of their applications, including gas separation and storage, chiral separation and structure determination, fluorescent sensing, heterogeneous catalysis, biological applications, proton conduction, photoluminescent materials, and membrane-based applications.

Hydrogen-Bonded Organic Frameworks as a Tunable Platform for Functional Materials.

The 31 P NMR spectra of triethylphosphine oxide (Et 3 PO) undergoes a shift upon interaction in solution with adjacent molecules. The oxygen of Et 3 PO is a strong electron donor and readily forms acid-base complexes with electron acceptors, with a consequent downfield shift in the 31 P NMR spectrum (Δδ ab ). We find that the 31 P NMR spectrum also is shifted downfield appreciably by van der Waals (largery dispersion force) interactions with solvents (Δδ d )

Spectral shifts in acid-base chemistry. II: Van der Waals contributions to acceptor numbers

An analytical model for spontaneous imbibition in fractal porous media including gravity

Poly(lactic acid) (PLA) is the most used biopolymer for food packaging applications. Several strategies have been made to improve PLA properties for extending its applications in the packaging field. Melt blending approaches are gaining considerable interest since they are easy, cost-effective and readily available processing technologies at the industrial level. With a similar melting temperature and high crystallinity, poly(hydroxybutyrate) (PHB) represents a good candidate to blend with PLA. The ability of PHB to act as a nucleating agent for PLA improves its mechanical resistance and barrier performance. With the dual objective to improve PLAPHB processing performance and to obtain stretchable materials, plasticizers are frequently added. Current trends to enhance PLA-PHB miscibility are focused on the development of composite and nanocomposites. PLA-PHB blends are also interesting for the controlled release of active compounds in the development of active packaging systems. This review explains the most relevant processing aspects of PLA-PHB based blends such as the influence of polymers molecular weight, the PLA-PHB composition as well as the thermal stability. It also summarizes the recent developments in PLA-PHB formulations with an emphasis on their performance with interest in the sustainable food packaging field. PLA-PHB blends shows highly promising perspectives for the replacement of traditional petrochemical based polymers currently used for food packaging.

On the Use of PLA-PHB Blends for Sustainable Food Packaging Applications

The coarse crystal layer growth and liquid entrapment processes were investigated with gradient freeze technology in this paper. The research system was hemihydrate phosphoric acid (H3PO4·0.5H2O) crystal-phosphoric acid aqueous solution. The distribution coefficients of ions (Ca 2+ ,F e 3+ and Na + ) in this system were measured. The effect of supercooling degree gradient on layer growth and the effect layer growth rate on ions redistribution were studied. The result indicated that the layer growth rate increased with supercooling degree gradient as an exponential curve. The distribution coefficient tended to increase as an approximate ‘S’ curve when coarse crystal layer growth rate increased. The ‘three region’ theory was applied to explain this phenomenon. Each ion’s diffusion parameter was obtained, which contributed to explain the separation differences between different ions. The work in this paper also indicated that layer crystallization was an effective separation technology for electronic grade phosphoric acid preparation.

Coarse crystal layer growth and liquid entrapment study with gradient freeze technology

Cefalexin crystallization residual liquor separation via nanofiltration based multistage process

Preparation and Dehydration Kinetics of Complex Sulfadiazine Calcium Hydrate with Both Channel-Type and Coordinated Water

The invention discloses a crystallizing method for preparing high-purity creatine phosphate sodium. The crystallizing method comprises the following steps of: dissolving a creatine phosphate sodium crude product in water to prepare a 0.5-1.1 g/ml creatine phosphate sodium aqueous solution, continuously stirring for 30-60 minutes to decolor; after filtering, transferring a filtrate into a crystallizer, controlling a system temperature to be within 5-45 DEG C, and adding an alcohol or ketone organic solvent to perform solvent-out crystallization; after crystallizing, and separating through filtering, washing with a solvent and drying to obtain a creatine phosphate sodium product. The creatine phosphate sodium crystal provided by the invention is high in crystallinity degree, complete in product crystal habit, and uniform in particle size distribution; and a primary particle size is 67.1-70.2 mu m. The product purity reaches more than 99.5%, and a single molar yield during the crystallizing process is more than 98.0%; and the method is simple in process, low in cost and suitable for industrial production.

Crystal preparation method of creatine phosphate sodium

Recently, there has been an increasing interest in spherulites because of their excellent physicochemical properties and remarkable radial morphologies. However, their formation mechanisms remain largely unresolved and are often overlooked in industrial crystallization. In this work, it was demonstrated that the sodium percarbonate (SPC) spherical particle primarily results from the spherulitic growth effect rather than agglomeration effect. And then, in situ nucleation-controlled experiments in Petri dish were established to study the growth kinetics and morphologies of SPC spherulite. During the process, a critical growth rate was first discovered, which divides the spherulite formation into branching and nonbranching stage. A kinetic model was established to study the growth regime for SPC spherulite formation. Moreover, it is found that sodium hexametaphosphate (SHMP) is not necessary for SPC spherulite, but it can promote the branching of SPC which makes it possible to produce compact SPC spherulite ...

Baohong Hou

Papers

Coarse crystal layer growth and liquid entrapment study with gradient freeze technology

Cefalexin crystallization residual liquor separation via nanofiltration based multistage process

Preparation and Dehydration Kinetics of Complex Sulfadiazine Calcium Hydrate with Both Channel-Type and Coordinated Water

Crystal preparation method of creatine phosphate sodium

Crystallization of Sodium Percarbonate from Aqueous Solution: Basic Principles of Spherulite Product Design