B
Beat Müllhaupt
Researcher at University of Zurich
Publications - 289
Citations - 17086
Beat Müllhaupt is an academic researcher from University of Zurich. The author has contributed to research in topics: Hepatitis C & Liver transplantation. The author has an hindex of 55, co-authored 258 publications receiving 14656 citations.
Papers
More filters
Journal ArticleDOI
Complement factor C5 deficiency significantly delays the progression of biliary fibrosis in bile duct-ligated mice.
Johannes Schmitt,Martin Roderfeld,Karim Sabrane,Pan Zhang,Yinghua Tian,Joachim C. Mertens,Pascal Frei,Bruno Stieger,Achim Weber,Beat Müllhaupt,Elke Roeb,Andreas Geier +11 more
TL;DR: C5 deficiency leads to attenuated inflammation and normalized MMP-9 activity concomitantly with a significant reduction of fibrosis, and appears to be an attractive target for future therapeutic intervention in chronic cholestatic liver disease.
Journal ArticleDOI
Pegylated interferon-alpha2a/ribavirin treatment of recurrent hepatitis C after liver transplantation.
S. Dinges,Isabelle Morard,Markus H. Heim,J-F Dufour,Beat Müllhaupt,Emiliano Giostra,P. A. Clavien,Gilles Mentha,Francesco Negro +8 more
TL;DR: A 48‐week course of pegylated IFN‐α2a/ribavirin therapy is effective in patients with recurrent HCV infection after LT, and the optimal schedule remains undetermined.
Journal ArticleDOI
A frequent hypofunctional IRAK2 variant is associated with reduced spontaneous hepatitis C virus clearance
Hui Wang,Souhayla El Maadidi,Janett Fischer,Elena Grabski,Sabine Dickhöfer,Sascha N. Klimosch,Sinead M. Flannery,Angela Filomena,Olaf Oliver Wolz,Nicole Schneiderhan-Marra,Markus W. Löffler,Manfred Wiese,Tica Pichulik,Beat Müllhaupt,David Semela,Jean-François Dufour,Pierre-Yves Bochud,Andrew G. Bowie,Ulrich Kalinke,Thomas Berg,Alexander N.R. Weber +20 more
TL;DR: This study discovered a comparatively frequent coding variant of the enigmatic human IRAK2, L392V, to be associated with a reduced ability to induce interferon‐alpha in primary human plasmacytoid dendritic cells in response to hepatitis C virus (HCV).
Journal ArticleDOI
Life-Threatening or Organ-Impairing Henoch-Schönlein Purpura: Plasmapheresis May Save Lives and Limit Organ Damage
Davide Donghi,Urs Schanz,Ulrike Sahrbacher,Mike Recher,Ralph M. Trüeb,Beat Müllhaupt,Lars E. French,Jürg Hafner +7 more
TL;DR: Adult-onset Henoch-Schönlein purpura tends to become chronic-relapsing, yet rarely leads to organ impairment, yet the growing literature on its highly beneficial effect underlines its potential usefulness.
Journal ArticleDOI
Epidemic cystic and alveolar echinococcosis in Kyrgyzstan: an analysis of national surveillance data
Giulia Paternoster,Gianluca Boo,Craig Wang,Gulnara Minbaeva,Jumagul Usubalieva,Kursanbek Mamasalievich Raimkulov,Abdykadyr Zhoroev,Kubanychbek K. Abdykerimov,Philipp A Kronenberg,Philipp A Kronenberg,Beat Müllhaupt,Reinhard Furrer,Peter Deplazes,Paul R. Torgerson +13 more
TL;DR: High-resolution maps identify precise locations where interventions and epidemiological research should be targeted to reduce the burden of human cystic echinococcosis and alveolar echinOCoccosis in Kyrgyzstan.