B
Bente Klarlund Pedersen
Researcher at University of Copenhagen
Publications - 713
Citations - 81605
Bente Klarlund Pedersen is an academic researcher from University of Copenhagen. The author has contributed to research in topics: Skeletal muscle & Insulin resistance. The author has an hindex of 134, co-authored 689 publications receiving 72177 citations. Previous affiliations of Bente Klarlund Pedersen include Health Science University & University of Copenhagen Faculty of Health Sciences.
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Journal ArticleDOI
Smoking impairs muscle protein synthesis and increases the expression of myostatin and MAFbx in muscle
A. M. W. Petersen,Faidon Magkos,Philip J. Atherton,Anna Selby,Kenneth Smith,Michael J. Rennie,Bente Klarlund Pedersen,Bettina Mittendorfer +7 more
TL;DR: It is concluded that smoking impairs the muscle protein synthesis process and increases the expression of genes associated with impaired muscle maintenance; smoking therefore likely increases the risk of sarcopenia.
Journal ArticleDOI
Impaired production of proinflammatory cytokines in response to lipopolysaccharide (LPS) stimulation in elderly humans
TL;DR: In this article, age-related changes in levels of early mediators of the acute-phase response in whole blood supernatants following LPS stimulation, representing an ex vivo model of sepsis, were investigated.
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Acute interleukin-6 administration does not impair muscle glucose uptake or whole-body glucose disposal in healthy humans.
Adam Steensberg,Christian P. Fischer,Massimo Sacchetti,Charlotte Keller,Takuya Osada,Peter Schjerling,Gerrit van Hall,Mark A. Febbraio,Mark A. Febbraio,Bente Klarlund Pedersen +9 more
TL;DR: It is demonstrated that acute IL‐6 administration does not impair whole‐body glucose disposal, net leg‐glucose uptake, or increase endogenous glucose production at rest in healthy young humans.
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Endurance training reduces the contraction-induced interleukin-6 mRNA expression in human skeletal muscle.
Christian P. Fischer,Peter Plomgaard,Anne K. Hansen,Henriette Pilegaard,Bengt Saltin,Bente Klarlund Pedersen +5 more
TL;DR: The magnitude of the exercise-induced IL-6 mRNA expression in contracting human skeletal muscle was markedly reduced by 10 wk of training.
Journal Article
Human T cell responses induced by vaccination with Mycobacterium bovis bacillus Calmette-Guérin.
TL;DR: The study shows that BCG vaccination of previously nonsensitized donors can provide important data on potentially protective immune responses in humans and suggest a careful evaluation of prevaccination sensitivity when investigating vaccine-induced immunity.