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Bente Klarlund Pedersen
Researcher at University of Copenhagen
Publications - 713
Citations - 81605
Bente Klarlund Pedersen is an academic researcher from University of Copenhagen. The author has contributed to research in topics: Skeletal muscle & Insulin resistance. The author has an hindex of 134, co-authored 689 publications receiving 72177 citations. Previous affiliations of Bente Klarlund Pedersen include Health Science University & University of Copenhagen Faculty of Health Sciences.
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Journal ArticleDOI
Prevalence and prognostic significance of infection with TT virus in patients infected with human immunodeficiency virus.
Jens Kaae Christensen,Jesper Eugen-Olsen,Marie Louise Buhl Sørensen,Henrik Ullum,Susanne Borum Gjedde,Bente Klarlund Pedersen,J. O. Nielsen,Kim Krogsgaard +7 more
TL;DR: The possible pathogenic role of TTV was investigated in patients infected with human immunodeficiency virus (HIV) and there was a correlation between lower CD4+ T cell counts and higher TTV titers.
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Proteome- and Transcriptome-Driven Reconstruction of the Human Myocyte Metabolic Network and Its Use for Identification of Markers for Diabetes
Leif Väremo,Camilla Scheele,Christa Broholm,Adil Mardinoglu,Caroline Kampf,Anna Asplund,Intawat Nookaew,Mathias Uhlén,Bente Klarlund Pedersen,Jens Nielsen,Jens Nielsen +10 more
TL;DR: Transcriptional changes were mapped on the myocyte GEM, revealing extensive transcriptional regulation in T2D, particularly around pyruvate oxidation, branched-chain amino acid catabolism, and tetrahydrofolate metabolism, connected through the downregulated dihydrolipoamide dehydrogenase.
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Skeletal muscle as a gene regulatory endocrine organ.
TL;DR: Skeletal muscle is an endocrine organ which, by the release of myokines, may influence metabolism in virtually all organs in the body and this knowledge may potentially open up for the possibility of designing new drugs that mimic the effects of the myokine signaling.
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Glucose ingestion attenuates the exercise-induced increase in circulating heat shock protein 72 and heat shock protein 60 in humans
Mark A. Febbraio,Jose L Mesa,Jason Chung,Adam Steensberg,Charlotte Keller,Henning B. Nielsen,Peter Krustrup,Peter Ott,Niels H. Secher,Bente Klarlund Pedersen +9 more
TL;DR: Keeping glucose availability during exercise attenuates the circulating Hsp response in healthy humans and neither exercise nor glucose ingestion affected the Hsp72 or Hsp60 protein expression in, or their release from, contracting skeletal muscle.
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Glucagon-to-insulin ratio is pivotal for splanchnic regulation of FGF-21 in humans
Jakob S. Hansen,Jens Otto Clemmesen,Niels H. Secher,Miriam Hoene,Andrea Drescher,Cora Weigert,Bente Klarlund Pedersen,Peter Plomgaard +7 more
TL;DR: It is demonstrated that the splanchnic circulation secretes FGF-21 at rest and that it is rapidly enhanced during exercise, and a dynamic interaction of glucagon-to-insulin ratio regulates F GF-21 secretion in humans.