Bernard Hirschel

TL;DR: No associations with mortality were found with any circulating miRNAs studied and these results cast doubt onto the effectiveness of circulating miRNA as early predictors of mortality or the major underlying diseases that contribute to mortality in participants treated for HIV-1 infection.

TL;DR: The view that, under certain conditions, fibroblasts can differentiate into a cell type structurally and functionally similar to smooth muscle and that this cell, the "myo-fibroblast," plays an important role in connective tissue contraction is supported.

TL;DR: These findings indicate that fibroblasts are able to modulate toward a cell type that is morphologically and functionally close to smooth muscle.

TL;DR: Individuals with incomplete CD4 T cell recovery to <500 cells/microL had more advanced HIV-1 infection at baseline and predicted, in conjunction with baseline CD 4 T cell count and age, incomplete response with 80% sensitivity and 72% specificity.

TL;DR: Stopping primary prophylaxis against P. carinii pneumonia appears to be safe in HIV-infected patients who are receiving combination antiretroviral treatment and who have had a sustained increase in their CD4 counts to at at least 200 cells per cubic millimeter and to at least 14 percent of total lymphocytes.