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Bettina Warscheid
Researcher at University of Freiburg
Publications - 209
Citations - 11650
Bettina Warscheid is an academic researcher from University of Freiburg. The author has contributed to research in topics: Translocase of the inner membrane & Proteome. The author has an hindex of 54, co-authored 192 publications receiving 9640 citations. Previous affiliations of Bettina Warscheid include Centre national de la recherche scientifique & University of Maryland, College Park.
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Book ChapterDOI
Cytoscape: software for visualization and analysis of biological networks.
TL;DR: This chapter focuses on software tools that assist in visual exploration and analysis of biological networks, exemplified using the widely used Cytoscape tool.
Journal ArticleDOI
Protein labeling by iTRAQ: A new tool for quantitative mass spectrometry in proteome research
TL;DR: A novel, MS‐based approach for the relative quantification of proteins, relying on the derivatization of primary amino groups in intact proteins using isobaric tag for relative and absolute quantitation (iTRAQ), which developed a quantitative strategy that comprises labeling of intact proteins by iTRAQ followed by gel electrophoresis and peptide MS/MS analyses.
Journal ArticleDOI
Mitochondrial proteins: from biogenesis to functional networks
TL;DR: How the mitochondrial protein import machinery functions as a key organizer of these protein networks, its involvement in the formation of membrane contact sites, and how defects in protein import can lead to disease are discussed.
Journal ArticleDOI
A systems study reveals concurrent activation of AMPK and mTOR by amino acids
Piero Dalle Pezze,Stefanie Ruf,Stefanie Ruf,Annika G Sonntag,Miriam Langelaar-Makkinje,Philip Hall,Alexander Martin Heberle,Patricia Razquin Navas,Patricia Razquin Navas,Karen van Eunen,Regine C Tölle,Jennifer J. Schwarz,Heike Wiese,Bettina Warscheid,Jana Deitersen,Björn Stork,Erik Fäßler,Sascha Schäuble,Udo Hahn,Peter Horvatovich,Daryl P. Shanley,Kathrin Thedieck,Kathrin Thedieck +22 more
TL;DR: It is found that aa acutely activate AMPK concurrently with mTOR, and it is shown that AMPK under aa sufficiency acts to sustain autophagy, which may be required to maintain protein homoeostasis and deliver metabolite intermediates for biosynthetic processes.
Journal ArticleDOI
Dual Role of Mitofilin in Mitochondrial Membrane Organization and Protein Biogenesis
Karina von der Malsburg,Judith M. Müller,Maria Bohnert,Silke Oeljeklaus,Paulina Kwiatkowska,Paulina Kwiatkowska,Thomas Becker,Adrianna Loniewska-Lwowska,Sebastian Wiese,Sanjana Rao,Dusanka Milenkovic,Dana P. Hutu,Ralf M. Zerbes,Agnes Schulze-Specking,Helmut E. Meyer,Jean-Claude Martinou,Sabine Rospert,Peter Rehling,Peter Rehling,Chris Meisinger,Marten Veenhuis,Bettina Warscheid,Ida J. van der Klei,Nikolaus Pfanner,Agnieszka Chacinska,Agnieszka Chacinska,Martin van der Laan +26 more
TL;DR: The findings indicate that mitofilin is a central component of MINOS and functions as a multifunctional regulator of mitochondrial architecture and protein biogenesis.