Blair R. Anderson

TL;DR: A recurrent 370‐kb deletion at the 22q11.2 locus is identified as a driver of kidney defects in the DiGeorge syndrome and in sporadic congenital kidney and urinary tract anomalies.

TL;DR: A novel paracrine mechanism whereby malignant hepatocytes produce Hh ligands to stimulate glycolysis in neighboring myofibroblasts, resulting in release of my ofibroblast-derived lactate that the malignant liver cells use as an energy source is identified.

TL;DR: Genetic and in vivo modeling studies indicate a critical role for APOL1 in renal function that is compromised by nephropathy-risk encoding variants and suggest that consideration of the context-dependent functions of both proteins will be required to develop therapeutic paradigms.

TL;DR: These data indicate that miRNAs differ between squamous esophageal epithelium and BE/EAC, but do not distinguish between BE and EAC, and suggest prospective evaluation of mi RNAs in patients at high risk for EAC.

TL;DR: Analysis of a male melanoma cell line and normal skin cells from the same individual confirmed that a transition in chromatin state occurred in response to transformation, and it was reported that the ubiquitous transcription factor YY1 associates with the euchromatic form of DXZ4 on the Xi.