Bob A. Rappaport

TL;DR: In this article, the authors provide recommendations for the core outcome domains that should be considered by investigators conducting clinical trials of the efficacy and effectiveness of treatments for chronic pain, and develop a core set of outcome domains would facilitate comparison and pooling of d

TL;DR: A consensus meeting was convened by the Initiative on Methods, Measurement, and Pain Assessment in Clinical Trials (IMMPACT) to provide recommendations for interpreting clinical importance of treatment outcomes in clinical trials of the efficacy and effectiveness of chronic pain treatments as discussed by the authors.

TL;DR: Based on systematic review and consensus of experts, core domains and measures for clinical trials to treat pain in children and adolescents were defined to assist in comparison and pooling of data and promote evidence-based treatment.

TL;DR: The data suggest that the SF‐MPQ‐2 has excellent reliability and validity, and the results of both exploratory and confirmatory factor analyses provided support for four readily interpretable subscales—continuous pain, intermittent pain, predominantly neuropathic pain, and affective descriptors.

TL;DR: The essential differences between the interpretation of the clinical importance of patient improvements and of group differences are described and the factors to consider are discussed, which include the results of responder analyses of the primary outcome measure and analyses of secondary efficacy endpoints.