Bon H. Verweij

TL;DR: It is demonstrated that sequencing of densely affected families permits exploration of the role of rare variants in a relatively common disease such as IA, although there are important study design considerations for applying sequencing to complex disorders.

TL;DR: Fewer patients tend to develop vasospasm after treatment with pTBA and there is a statistically significantly decreased need for therapeutic angioplasty, and proof of concept is confirmed by these results.

TL;DR: Clinical outcome of aneurysmal subarachnoid hemorrhage patients with DCI included in a randomized trial on the effectiveness of induced hypertension does not add any evidence to support induced hypertension and shows that this treatment can lead to serious adverse events.

TL;DR: Irregular aneurysm shape was identified as a risk factor with potential for use in clinical practice and the risk factors aspect ratio, size ratio, bottleneck factor, height-to-width ratio, contact with the perianeurysmal environment, volume- to-ostium ratio, and dome-direction should first be confirmed in multivariate analysis and incorporated in prediction models.

TL;DR: This study shows that the excimer laser-assisted nonocclusive anastomosis high-flow replacement bypass is a reliable and effective method to treat these otherwise untreatable patients.