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Brenda E. Porter
Researcher at Stanford University
Publications - 87
Citations - 3143
Brenda E. Porter is an academic researcher from Stanford University. The author has contributed to research in topics: Epilepsy & Epilepsy surgery. The author has an hindex of 29, co-authored 77 publications receiving 2628 citations. Previous affiliations of Brenda E. Porter include Washington University in St. Louis & University of Pennsylvania.
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Journal ArticleDOI
Report of a parent survey of cannabidiol-enriched cannabis use in pediatric treatment-resistant epilepsy.
TL;DR: It is shown that parents are using cannabidiol-enriched cannabis as a treatment for their children with treatment-resistant epilepsy, and objective measurements of a standardized preparation of pure cannABidiol are needed to determine whether it is safe, well tolerated, and efficacious at controlling seizures.
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Primary sequence of a motor neuron-selective adhesive site in the synaptic basal lamina protein S-laminin
Dale D. Hunter,Brenda E. Porter,Joseph W. Bulock,Steven Paul Adams,John P. Merlie,Joshua R. Sanes +5 more
TL;DR: Recombinant fragments are used to localize a neuronal attachment site to the C-terminal 10% of s-laminin and identify the primary sequence of the adhesive site as Leu-Arg-Glu (LRE): neurons attach to an immobilized LRE-containing peptide, and soluble LRE blocks attachment of neurons to the s- laminin fragment.
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KCNQ2 encephalopathy: Features, mutational hot spots, and ezogabine treatment of 11 patients.
John Millichap,Kristen Park,Tammy Tsuchida,Bruria Ben-Zeev,Lionel Carmant,Robert Flamini,Nishtha Joshi,Paul M. Levisohn,Eric D. Marsh,Srishti Nangia,Vinodh Narayanan,Xilma R. Ortiz-Gonzalez,Marc C. Patterson,Phillip L. Pearl,Brenda E. Porter,Keri Ramsey,Emily L. McGinnis,Maurizio Taglialatela,Molly Tracy,Baouyen Tran,Charu Venkatesan,Sarah Weckhuysen,Edward C. Cooper +22 more
TL;DR: This study provides Class IV evidence that EZO is effective for refractory seizures in patients with epilepsy due to KCNQ2 encephalopathy and assesses the potential of selectiveKCNQ channel openers as targeted treatments.
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A motoneuron-selective stop signal in the synaptic protein S-laminin
TL;DR: It is reported that a recombinant s-laminin fragment inhibits neurite outgrowth promoted by laminin, and a tripeptide sequence in this fragment, Leu-Arg-Glu (LRE), contributes to this inhibition and is itself sufficient to inhibit outgrowth.
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The perineuronal net component of the extracellular matrix in plasticity and epilepsy
TL;DR: An overview of the ECM and PN in the CNS will be presented with special emphasis on potential roles in epileptogenesis.