B
Brigitte Schlegelberger
Researcher at University of Kiel
Publications - 94
Citations - 4159
Brigitte Schlegelberger is an academic researcher from University of Kiel. The author has contributed to research in topics: Fluorescence in situ hybridization & Chromosomal translocation. The author has an hindex of 30, co-authored 94 publications receiving 4079 citations. Previous affiliations of Brigitte Schlegelberger include Hannover Medical School.
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A physical map of the human genome.
John Douglas Mcpherson,Marco A. Marra,Marco A. Marra,LaDeana W. Hillier,Robert H. Waterston,Asif T. Chinwalla,John W. Wallis,Mandeep Sekhon,Kristine M. Wylie,Elaine R. Mardis,Richard K. Wilson,Robert S. Fulton,Tamara A. Kucaba,Caryn Wagner-McPherson,William B. Barbazuk,Simon G. Gregory,Sean Humphray,Lisa French,R Evans,Graeme Bethel,Adam Whittaker,Jane L. Holden,Owen T. McCann,Andrew Dunham,Carol Soderlund,Carol Scott,David R. Bentley,Gregory D. Schuler,Hsiu Chuan Chen,Wonhee Jang,Eric D. Green,Jacquelyn R. Idol,Valerie Maduro,Kate Montgomery,Eunice Lee,Ashley Miller,Suzanne Emerling,Raju Kucherlapati,Richard A. Gibbs,Steve Scherer,J. Harley Gorrell,Erica Sodergren,Kerstin P. Clerc-Blankenburg,Paul E. Tabor,S. Naylor,Dawn Garcia,J. de Jong,J. de Jong,J. de Jong,Joseph J. Catanese,Joseph J. Catanese,Joseph J. Catanese,Norma J. Nowak,Kazutoyo Osoegawa,Kazutoyo Osoegawa,Kazutoyo Osoegawa,Shizhen Qin,Lee Rowen,Anuradha Madan,Monica Dors,Leroy Hood,Barbara J. Trask,Cynthia Friedman,Hillary Massa,Vivian G. Cheung,Ilan R. Kirsch,Thomas Reid,Raluca Yonescu,Jean Weissenbach,Thomas Brüls,Roland Heilig,Elbert Branscomb,Anne S. Olsen,Norman A. Doggett,Jan Fang Cheng,Trevor Hawkins,Richard M. Myers,Jin Shang,Lucía Ramírez,Jeremy Schmutz,Olivia Velasquez,Kami Dixon,Nancy E. Stone,David R. Cox,David Haussler,W. James Kent,Terrence S. Furey,Sanja Rogic,Scot Kennedy,Steven J.M. Jones,André Rosenthal,Gaiping Wen,Markus Schilhabel,Gernot Gloeckner,Gerald Nyakatura,Reiner Siebert,Brigitte Schlegelberger,Julie R. Korenberg,Xiao Ning Chen,Asao Fujiyama,Masahira Hattori,Atsushi Toyoda,Tetsushi Yada,Hong Seok Park,Yoshiyuki Sakaki,Nobuyoshi Shimizu,Shuichi Asakawa,Kazuhiko Kawasaki,Takashi Sasaki,Ai Shintani,Atsushi Shimizu,Kazunori Shibuya,Jun Kudoh,Shinsei Minoshima,Juliane Ramser,Peter Seranski,Céline Hoff,Annemarie Poustka,Richard Reinhardt,Hans Lehrach +119 more
TL;DR: The construction of the whole-genome bacterial artificial chromosome (BAC) map and its integration with previous landmark maps and information from mapping efforts focused on specific chromosomal regions are reported.
Journal ArticleDOI
Inactivating mutations and overexpression of BCL10, a caspase recruitment domain-containing gene, in MALT lymphoma with t(1;14)(p22;q32).
Quangeng Zhang,Reiner Siebert,Minhong Yan,Bernd Hinzmann,Xiaoli Cui,Liquan Xue,Karen M. Rakestraw,Clayton W. Naeve,Georg Beckmann,Dennis D. Weisenburger,Warren G. Sanger,Hadwiga Nowotny,Michael Vesely,Evelyne Callet-Bauchu,Gilles Salles,Vishva M. Dixit,André Rosenthal,Brigitte Schlegelberger,Stephan W. Morris,Stephan W. Morris +19 more
TL;DR: Mucosa-associated lymphoid tissue (MALT) lymphomas most frequently involve the gastrointestinal tract and are the most common subset of extranodal non-Hodgkin lymphoma (NHL), and overexpression of BCL10, a novel apoptotic signalling gene that encodes an amino-terminal caspase recruitment domain (CARD), in MALT lymphomas might have a twofold lymphomagenic effect.
Journal ArticleDOI
Patients with de novo acute myeloid leukaemia and complex karyotype aberrations show a poor prognosis despite intensive treatment: a study of 90 patients
Claudia Schoch,Torsten Haferlach,Detlef Haase,Christa Fonatsch,Helmut Löffler,Brigitte Schlegelberger,Peter Staib,Maria Cristina Sauerland,Achim Heinecke,Thomas Büchner,Wolfgang Hiddemann +10 more
TL;DR: In conclusion, complex chromosome aberrations in de novo AML predicted a dismal outcome, even when patients were treated with intensive chemotherapy, and patients under the age of 60’years with complex aberrant karyotypes may benefit from HAM treatment during induction.
Journal ArticleDOI
Simultaneous fluorescence immunophenotyping and interphase cytogenetics: a contribution to the characterization of tumor cells.
TL;DR: Using this method, numerically aberrant tumor cells can be identified by interphase cytogenetics and subsequently analyzed immunophenotypically, and since all interphase cellsCan be analyzed, the results are not limited by the number and banding quality of analyzable mitoses.
Journal ArticleDOI
Molecular cytogenetic delineation of a novel critical genomic region in chromosome bands 11q22.3-923.1 in lymphoproliferative disorders.
Stephan Stilgenbauer,Peter Liebisch,Michael R. James,Martin Schröder,Brigitte Schlegelberger,K. Fischer,Martin Bentz,Peter Lichter,Hartmut Döhner +8 more
TL;DR: A single critical region of 2-3 Mb in size is identified in which 11q14-923 aberrations in LPD cluster are identified, providing the basis for the identification of the gene(s) at 11q22.3- 923.1 that are involved in the pathogenesis of LPD.