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Bruce Neal
Researcher at The George Institute for Global Health
Publications - 620
Citations - 109123
Bruce Neal is an academic researcher from The George Institute for Global Health. The author has contributed to research in topics: Population & Blood pressure. The author has an hindex of 108, co-authored 561 publications receiving 87213 citations. Previous affiliations of Bruce Neal include National Institutes of Health & University of the Western Cape.
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Journal ArticleDOI
Interpretation of the evidence for the efficacy and safety of statin therapy.
Rory Collins,Christina Reith,Jonathan Emberson,Jane Armitage,Colin Baigent,Lisa Blackwell,Roger S. Blumenthal,John Danesh,George Davey Smith,David L. DeMets,Stephen J. W. Evans,Malcolm Law,Stephen MacMahon,Seth S. Martin,Bruce Neal,Neil R Poulter,David Preiss,Paul M. Ridker,Ian Roberts,Anthony Rodgers,Peter Sandercock,Kenneth F. Schulz,Peter S. Sever,John Simes,Liam Smeeth,Nicholas J. Wald,Salim Yusuf,Richard Peto +27 more
TL;DR: The large-scale evidence from randomised trials indicates that it is unlikely that large absolute excesses in other serious adverse events still await discovery, and any further findings that emerge about the effects of statin therapy would not be expected to alter materially the balance of benefits and harms.
Journal ArticleDOI
Rapid blood-pressure lowering in patients with acute intracerebral hemorrhage
Craig S. Anderson,Emma Heeley,Yining Huang,Jiguang Wang,Christian Stapf,Candice Delcourt,Richard I. Lindley,Thompson G. Robinson,Pablo M. Lavados,Pablo M. Lavados,Bruce Neal,Jun Hata,Jun Hata,Hisatomi Arima,Mark W Parsons,Yuechun Li,J. Wang,Stephane Heritier,Qiang Li,Mark Woodward,Mark Woodward,R. John Simes,Stephen M. Davis,John Chalmers +23 more
TL;DR: In patients with intracerebral hemorrhage, intensive lowering of blood pressure did not result in a significant reduction in the rate of the primary outcome of death or severe disability, and an ordinal analysis of modified Rankin scores indicated improved functional outcomes with intensive loweringof blood pressure.
Journal ArticleDOI
Intensive glucose control and macrovascular outcomes in type 2 diabetes
Fiona Turnbull,Carlos Abraira,Robert J. Anderson,Robert J. Anderson,Robert P. Byington,John Chalmers,William C. Duckworth,Gregory W. Evans,Hertzel C. Gerstein,Rury R. Holman,Thomas E. Moritz,Bruce Neal,Toshiharu Ninomiya,Anushka Patel,Sanjoy K. Paul,F. Travert,Mark Woodward,Mark Woodward +17 more
TL;DR: Targeting more-intensive glucose lowering modestly reduced major macrovascular events and increased major hypoglycaemia over 4.4 years in persons with type 2 diabetes, and suggests that glucose-lowering regimens should be tailored to the individual.
Journal ArticleDOI
Prevention of pulmonary embolism and deep vein thrombosis with low dose aspirin: Pulmonary Embolism Prevention (PEP) trial
Jeremy L. O'Brien,H Duncan,George Kirsh,V Allen,P King,R Hargraves,L. Mendes,T Perera,P Catto,Steven R. Schofield,H Ploschke,T Hefner,M Churchland,S Woolnough,R Wuttke,Maurice Manning,T Jeffries,L Hensley,Philip M.W. Bath,D Bainbridge,F Guinane,L McMahon,D Zavattaro,David Wilson,K Blake,J Morton,D Sharman,R Locke,J Ghabrial,S McNeil,P Rehfisch,S van der Merwe,B Einoder,D. Douglas,J Ashwell,A Morrissey,Alex Brown,R Simm,G Fisch,W Crawford,T Everding,D Tanham,J Hooper,C Aldana,M Goldwasser,M Mibus,Neville Rowden,J Mills,P Johnson,J Stilwell,Richard S. Williams,T Stevenson,J Zwar,R Bauze,B Nyunt,R Russell,G Day,M Cameron,P Clements,Thomas J. Beck,A Ellis,S Phipps,W Quaill,A Skirving,M McGuiness,P Gray,J Rankin,David A. Wood,J.,B Courtenay,Martin S. Green,Ian A. Harris,J Rush,M Kilgour,J Davies,J Newcombe,C Lewis,S Leitl,R Chilcott,R Pianta,A Aguila,C Hawe,S Nade,Mari Smith,P Robertson,A Rothwell,S May,Steven Williams,S Shamy,G Martin,V Steele,Kathryn J. Jeffery,I Kelman,J McKillan,P Dayaram,J Culling,D Lawson,P Winfield,R Kuzel,C Milburn,N Palmer,A Pitts,G Lamb,L Prodan,Harley Gray,K Walker,Kenneth Smith,Charles R. Newton,D Atkinson,B Fail,A Panting,J Menzies,A Watkiss,J Outhred,D Clay,R Lander,R Fou,D S Clarke,T Murrell,B Rolleston,S Keyworth,P Medlicott,T Woods,C Dawe,R Waldron,W Taine,L Le Roy,Andrew Smith,G Cowley,Colin A. Campbell,R Maxwell,M Elvy,Allen Thurston,S Newth,L Cousins,M Sanderson,C MacMillan,R Golele,J Walters,S Kruger,T Ramsden,H Joseph,D Gantz,S Steyn,S Hadjichristofis,L Nojoko,R Snowdowne,M Botha,R Knebel,I Sernbo,B Ferris,E Tello,A Nevelos,C Dunn,D Warwick,J Sudhakar,J D Tuite,Jobbin Francis,M E Wallace,A Jordan,P Baird,W Fowler,Ainscow Dap.,A Harrison,A Butler-Manuel,G Broome,P Swailes,T J Stahl,A M Randall,A J Forester,J Hucker,J Redden,L Logan,P W Howard,D Brownlee,P Angus,A Boyce,B B Porter,M Arbid,J Youll,A S Ogden,C MacDowell,M Beverly,P Ramdeholl,I Nelson,I Howlett,A Weeber,A Peacock,Hubbard Mjs.,M Flanagan,C Crawshaw,A Kinninmonth,T. Campbell,S Tibrewal,Lennox Cme.,I Clifford,N Gillham,M Hunt,C Bulstrode,R Handley,Vishwanath R. Iyer,J Lawton,J Robbins,W M Harper,J Davison,P Hope,K Smallbones,W. C. Jones,K R Ratnam,J Upton,P Hirst,S Knox,T Sadique,Mohammad Saud Khan,M Umar,Joshua T. Anderson,J Frank,Peter J. Briggs,P Sanderson,D McBride,K Leese,N C Bayliss,M El-Deen,H Banan,Michael Parker,H Minhas,A Best,C Blakeway,T Salter,M A Foy,A Pollitt,Blayney Jdm.,Stephen M. Davis,E Parnell,C Ko,M L Grover,S Howells,David J. Williams,C Saunders,I Brenkel,G Mani,M Grizzle,A Henderson,T Board,C J Chadwick,M Overton,S Hodkinson,D A Macdonald,V Lewis,McDonald Rjm.,J Adamson,J Bradley,E Hodgson,J L Plewes,D Clarke,M Hullin,Jason M. Smith,G J Lemon,K Greatrex,C Miles,G Bannister,J Dare,D G Carden,J Aughton,A Stirrat,J Fishburn,A O Ebizie,M Mason,G Irvine,T Facey,C Spratt,N Kanagavel,T Gerrard,N Reissis,P Tzanetos,M Stefanotti,M Greiss,V Wright,A Rahmaty,John Archer,A Bedford,David Taylor,M Griffith,Jennifer R Evans,K Heron,B Livingstone,K O'Dwyer,David J. Wheatley,P Campbell,P Dixon,L McSweeney,Shanahan Mdg.,I Griffith,Stephen MacMahon,Anthony Rodgers,Rory Collins,C Prentice,Robyn Norton,P Ockleford,M Rutland,J Dickinson,P Gregg,D Macdonald,Mollan Rab.,J. Douglas,D Beaumont,Joanna Broad,Taane G. Clark,M. A. Henderson,A McCulloch,Bruce Neal,Rajendra Prasad,Natalie Walker,M Wood,A Beighton,P Bell,Barbara Farrell,K Murch,Norman Sharpe,Gary Gordon,Robert N. Doughty,Yogini Ratnasabapathy,John Danesh,Peter Sleight,Richard Peto,John Simes,Anthony C Keech,Tri Pep. +327 more
TL;DR: In this article, a meta-analysis of their results indicated reductions in the risks of deep-vein thrombosis and of pulmonary embolism in various high-risk groups.
Journal ArticleDOI
Effects of blood pressure lowering with perindopril and indapamide therapy on dementia and cognitive decline in patients with cerebrovascular disease.
Christophe Tzourio,Craig S. Anderson,Neil Chapman,Mark Woodward,Bruce Neal,Stephen MacMahon,John Chalmers +6 more
TL;DR: Findings further support the recommendation that blood pressure lowering with perindopril and indapamide therapy be considered for all patients with cerebrovascular disease.