C. Dreyfus

TL;DR: Using consensus degenerate RT-PCR, a novel influenza A virus is identified in a flat-faced fruit bat from Peru, indicating that bats constitute a potentially important and likely ancient reservoir for a diverse pool of influenza viruses.

TL;DR: Two antibodies, which bind to distinct regions of the viral hemagluttinin (HA) molecule, neutralize multiple strains from both lineages of influenza B virus, whereas the third antibody binds to the stem region of HA and is able to neutralize both influenza A and B strains.

TL;DR: In this paper, a general computational method for designing proteins that bind a surface patch of interest on a target macromolecule was described, and two of the designed proteins, HB36 and HB80, bind H1 and H5 HAs with low nanomolar affinity.

TL;DR: The most potent of these inhibitors, a 51-residue protein, is broadly cross-reactive against all influenza group 1 hemagglutinins, including human H2, and neutralizes H1N1 viruses with a potency that rivals that of several human monoclonal antibodies, demonstrating that computational design followed by comprehensive energy landscape mapping can generate proteins with potential therapeutic utility.

TL;DR: The crystal structure of mouse antibody C179 bound to the pandemic 1957 H2N2 hemagglutinin reveals that it targets an epitope on the HA stem similar to those targeted by the recently identified human broadly neutralizing antibodies.