C
Chanseok Shin
Researcher at Seoul National University
Publications - 59
Citations - 10631
Chanseok Shin is an academic researcher from Seoul National University. The author has contributed to research in topics: Gene silencing & RNA. The author has an hindex of 25, co-authored 54 publications receiving 9686 citations. Previous affiliations of Chanseok Shin include Massachusetts Institute of Technology & Columbia University.
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Journal ArticleDOI
The impact of microRNAs on protein output
TL;DR: The impact of micro RNAs on the proteome indicated that for most interactions microRNAs act as rheostats to make fine-scale adjustments to protein output.
Journal ArticleDOI
Passenger-strand cleavage facilitates assembly of siRNA into Ago2-containing RNAi enzyme complexes
TL;DR: It is shown that Ago2 instead directly receives the double-stranded siRNA from the RISC assembly machinery, and then cleaves the siRNA passenger strand, thereby liberating the single-Stranded guide.
Journal ArticleDOI
Genome sequence of the hot pepper provides insights into the evolution of pungency in Capsicum species
Seungill Kim,Minkyu Park,Seon-In Yeom,Yong-Min Kim,Je Min Lee,Hyun-Ah Lee,Eunyoung Seo,Jaeyoung Choi,Kyeongchae Cheong,Ki-Tae Kim,Kyongyong Jung,Gir-Won Lee,Sang-Keun Oh,Chungyun Bae,Saet-Byul Kim,Hyeyoung Lee,Shin Young Kim,Myung-Shin Kim,Byoung-Cheorl Kang,Yeong Deuk Jo,Hee Bum Yang,Hee-Jin Jeong,Won-Hee Kang,Jin Kyung Kwon,Chanseok Shin,Jae Yun Lim,June Hyun Park,Jin Hoe Huh,June Sik Kim,Byung-Dong Kim,Oded Cohen,Ilan Paran,Mi Chung Suh,Saet Buyl Lee,Yeon Ki Kim,Younhee Shin,Seung-Jae Noh,Junhyung Park,Young Sam Seo,Suk-Yoon Kwon,Hyun A Kim,Jeong Mee Park,Hyunjin Kim,Sang Bong Choi,Paul W. Bosland,Gregory Reeves,Sung Hwan Jo,Bong Woo Lee,Hyung-Taeg Cho,Hee-Seung Choi,Min-Soo Lee,Yeisoo Yu,Yang Do Choi,Beom Seok Park,Allen Van Deynze,Hamid Ashrafi,Theresa Hill,Woo Taek Kim,Hyun Sook Pai,Hee-Kyung Ahn,Inhwa Yeam,James J. Giovannoni,James J. Giovannoni,Jocelyn K. C. Rose,Iben Sørensen,Sang Jik Lee,Ryan W. Kim,Ik-Young Choi,Beom-Soon Choi,Jong-Sung Lim,Yong-Hwan Lee,Doil Choi +71 more
TL;DR: The genome size of the hot pepper was approximately fourfold larger than that of its close relative tomato, and the genome showed an accumulation of Gypsy and Caulimoviridae family elements.
Journal ArticleDOI
Weak seed-pairing stability and high target-site abundance decrease the proficiency of lsy-6 and other microRNAs
TL;DR: In this article, the authors used the TargetScan tool for quantitatively predicting miRNA regulation (and siRNA off-targeting) to model differential miRNA proficiencies, thereby improving prediction performance.
Weak seed-pairing stability and high target-site abundance decrease the proficiency of lsy-6 and other microRNAs
TL;DR: The TargetScan tool is expanded to model differential miRNA regulation (and siRNA off-targeting) proficiencies to improve prediction performance and it is proposed that siRNAs designed to have both weaker SPS and higher TA will have fewer off-targets without compromised on-target activity.