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Chao Li
Researcher at University of Texas Southwestern Medical Center
Publications - 25
Citations - 653
Chao Li is an academic researcher from University of Texas Southwestern Medical Center. The author has contributed to research in topics: Mineralocorticoid receptor & Pressure overload. The author has an hindex of 12, co-authored 22 publications receiving 392 citations. Previous affiliations of Chao Li include Chinese Academy of Sciences & Shanghai Jiao Tong University.
Papers
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Journal ArticleDOI
T-Cell Mineralocorticoid Receptor Controls Blood Pressure by Regulating Interferon-Gamma
Xue Nan Sun,Chao Li,Yuan Liu,Lin-Juan Du,Meng-Ru Zeng,Xiao Jun Zheng,Wu Chang Zhang,Yan Liu,Mingjiang Zhu,Deping Kong,Li Zhou,Limin Lu,Zhu-Xia Shen,Yi Yi,Lili Du,Mu Qin,Xu Liu,Zichun Hua,Shuyang Sun,Huiyong Yin,Bin Zhou,Ying Yu,Zhiyuan Zhang,Sheng-Zhong Duan +23 more
TL;DR: In this article, the role of T-cell mineralocorticoid receptor (MR) deficiency in blood pressure regulation has been elucidated and the mechanism of the effect of MR deficiency on T cells has been explored.
Journal ArticleDOI
Association of the carboxyl-terminal PDZ ligand of neuronal nitric oxide synthase gene with schizophrenia in the Chinese Han population.
Yonglan Zheng,Huafang Li,Wei Qin,Wei Qin,Wuyan Chen,Wuyan Chen,Yun Duan,Yun Duan,Yue Xiao,Yue Xiao,Chao Li,Chao Li,Jing Zhang,Jing Zhang,Xingwang Li,Xingwang Li,Guoyin Feng,Lin He +17 more
TL;DR: The findings indicate that CAPON gene may be a candidate susceptibility gene for schizophrenia in Chinese Han population, and also provide further support for the potential importance of NMDAR-mediated glutamatergic transmission in the etiology of schizophrenia.
Journal ArticleDOI
Mineralocorticoid Receptor Deficiency in Macrophages Inhibits Neointimal Hyperplasia and Suppresses Macrophage Inflammation Through SGK1-AP1/NF-κB Pathways
Jian-Yong Sun,Chao Li,Zhu-Xia Shen,Wu-Chang Zhang,Tang-Jun Ai,Lin-Juan Du,Yuyao Zhang,Gao-Feng Yao,Yan Liu,Shuyang Sun,Anikó Náray-Fejes-Tóth,Géza Fejes-Tóth,Yong Peng,Mao Chen,Xiaojing Liu,Jun Tao,Bin Zhou,Ying Yu,Feifan Guo,Jie Du,Sheng-Zhong Duan +20 more
TL;DR: Selective deletion of MR in myeloid cells limits macrophage accumulation and vascular inflammation and, therefore, inhibits neointimal hyperplasia and vascular remodeling.
Journal ArticleDOI
Mineralocorticoid Receptor Deficiency in T Cells Attenuates Pressure Overload–Induced Cardiac Hypertrophy and Dysfunction Through Modulating T-Cell Activation
Chao Li,Xue-Nan Sun,Meng-Ru Zeng,Xiao-Jun Zheng,Yu-Yao Zhang,Qiangyou Wan,Wu-Chang Zhang,Chaoji Shi,Lin-Juan Du,Tang-Jun Ai,Yuan Liu,Yan Liu,Lili Du,Yi Yi,Ying Yu,Sheng-Zhong Duan +15 more
TL;DR: It is found that MR antagonist suppressed abdominal aortic constriction–induced cardiac hypertrophy and decreased the accumulation and activation of CD4+ and CD8+ T cells in mouse heart.
Journal ArticleDOI
Myeloid mineralocorticoid receptor deficiency inhibits aortic constriction-induced cardiac hypertrophy in mice.
Chao Li,Yu Yao Zhang,Ryan A. Frieler,Xiao Jun Zheng,Wu Chang Zhang,Xue Nan Sun,Qing Zhen Yang,Shu Min Ma,Baozhuan Huang,Stefan Berger,Wang Wang,Yong Wu,Ying(余鹰) Yu,ShengZhong(段胜仲) Duan,Richard M. Mortensen +14 more
TL;DR: It is indicated that MR deficiency in myeloid cells effectively attenuated aortic constriction-induced cardiac hypertrophy and fibrosis, as well as aortsic fibrosis and inflammation.