Yonglan Zheng

TL;DR: It is demonstrated that common schizophrenia susceptibility alleles can be detected and the characterization of these signals will suggest important directions for research on susceptibility mechanisms.

TL;DR: The identification of somatic mutations for GBC in 57 tumor-normal pairs through a combination of exome sequencing and ultra-deep sequencing of cancer-related genes provides insight into the somatic mutational landscape and highlights the key role of the ErbB signaling pathway in GBC pathogenesis.

TL;DR: A meta-analysis to examine the association of >3.2 million SNPs with BMI in 39,144 men and women of African ancestry and followed up the most significant associations in an additional 32,268 individuals ofAfrican ancestry provides strong support for shared BMI loci across populations, as well as for the utility of studying ancestrally diverse populations.

TL;DR: It is reported that hypermethylation of the CpG island 5' of the G4C2 repeat is associated with the presence of the expansion, bringing to question the current cutoff of 30 repeats for pathological alleles.

TL;DR: Patients diagnosed with primary invasive breast cancer and with personal or family cancer history or tumor characteristics associated with high genetic risk for all classes of germline mutations in known breast cancer susceptibility genes are evaluated using a validated targeted capture and multiplex sequencing approach.