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Charlotte Odendall
Researcher at King's College London
Publications - 22
Citations - 1948
Charlotte Odendall is an academic researcher from King's College London. The author has contributed to research in topics: Medicine & Biology. The author has an hindex of 13, co-authored 17 publications receiving 1686 citations. Previous affiliations of Charlotte Odendall include Boston Children's Hospital & Imperial College London.
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Journal ArticleDOI
Peroxisomes are signaling platforms for antiviral innate immunity
Evelyn Dixit,Steeve Boulant,Yijing Zhang,Amy S. Lee,Charlotte Odendall,Bennett O.V. Shum,Nir Hacohen,Zhijian J. Chen,Sean P. J. Whelan,Marc Fransen,Max L. Nibert,Giulio Superti-Furga,Jonathan C. Kagan +12 more
TL;DR: It is reported that the RIG-I-like receptor (RLR) adaptor protein MAVS is located on peroxisomes and mitochondria and it is found thatperoxisomal and mitochondrial MAVS act sequentially to create an antiviral cellular state.
Journal ArticleDOI
Diverse intracellular pathogens activate type III interferon expression from peroxisomes
Charlotte Odendall,Evelyn Dixit,Fabrizia Stavru,Hélène Bierne,Kate M Franz,Ann Fiegen Durbin,Steeve Boulant,Lee Gehrke,Pascale Cossart,Jonathan C. Kagan +9 more
TL;DR: It is revealed that the process of intestinal epithelial cell differentiation upregulates peroxisome biogenesis and promotes robust type III interferon responses in human cells, highlighting the importance of different intracellular organelles in specific innate immune responses.
Diverse intracellular pathogens activate type III interferon expression from peroxisomes
Charlotte Odendall,Evelyn Dixit,Fabrizia Stavru,Hélène Bierne,Kate M Franz,Ann Fiegen Durbin,Steeve Boulant,Lee Gehrke,Pascale Cossart,Jonathan C. Kagan +9 more
TL;DR: The authors found that RIG-I like receptors (RLRs) induce type III interferon expression in a variety of human cell types, and identified factors that differentially regulate expression of type I and type 3 interferons.
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COVID-19 and emerging viral infections: The case for interferon lambda.
Ludmila Prokunina-Olsson,Noémie Alphonse,Noémie Alphonse,Ruth E Dickenson,Joan E. Durbin,Jeffrey S. Glenn,Rune Hartmann,Sergei V. Kotenko,Helen M. Lazear,Thomas R. O'Brien,Charlotte Odendall,Olusegun O. Onabajo,Helen Piontkivska,Deanna M. Santer,Nancy C. Reich,Andreas Wack,Ivan Zanoni +16 more
TL;DR: The Viewpoint discusses the benefits and potential limitations of using interferon lambda (IFN-λ, a type III interferons) to prevent, limit, and treat COVID-19.
Journal ArticleDOI
SteC is a Salmonella kinase required for SPI-2-dependent F-actin remodelling
TL;DR: It is concluded that SPI‐2‐dependent F‐actin meshwork formation depends on the kinase activity of SteC, which resembles more closely eukaryotic than prokaryotic kinases.