Chris Boursnell

TL;DR: The definition and use of family-specific, manually curated gathering thresholds are explained and some of the features of domains of unknown function (also known as DUFs) are discussed, which constitute a rapidly growing class of families within Pfam.

TL;DR: TransRate is a tool for reference-free quality assessment of de novo transcriptome assemblies using only the sequenced reads and the assembly as input and it is revealed that variance in the quality of the input data explains 43% of the variance inThe quality of published de noVO transcriptome assembly assemblies.

TL;DR: TransRate can accurately evaluate assemblies of conserved and novel RNA molecules of any kind in any species and is more accurate than comparable methods and demonstrates its use on a variety of data.

TL;DR: Imaging of hyperpolarized [1-13C]pyruvate metabolism in breast cancer is feasible and demonstrated significant intertumoral and intratumoral metabolic heterogeneity, where lactate labeling correlated with MCT1 expression and hypoxia.

TL;DR: Insight is provided into the molecular function of this cell type in C3 species Arabidopsis thaliana, and characteristics of BS cells that are probably ancestral to both C3 and C4 plants are identified.