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Chris Boursnell
Researcher at University of Cambridge
Publications - 12
Citations - 15046
Chris Boursnell is an academic researcher from University of Cambridge. The author has contributed to research in topics: Breast cancer & Gene. The author has an hindex of 7, co-authored 11 publications receiving 14500 citations. Previous affiliations of Chris Boursnell include Wellcome Trust Sanger Institute.
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Journal ArticleDOI
The Pfam protein families database
Marco Punta,Penny Coggill,Ruth Y. Eberhardt,Jaina Mistry,John Tate,Chris Boursnell,Ningze Pang,Kristoffer Forslund,Goran Ceric,Jody Clements,Andreas Heger,Liisa Holm,Erik L. L. Sonnhammer,Sean R. Eddy,Alex Bateman,Robert D. Finn +15 more
TL;DR: The definition and use of family-specific, manually curated gathering thresholds are explained and some of the features of domains of unknown function (also known as DUFs) are discussed, which constitute a rapidly growing class of families within Pfam.
Journal ArticleDOI
TransRate: reference-free quality assessment of de novo transcriptome assemblies
TL;DR: TransRate is a tool for reference-free quality assessment of de novo transcriptome assemblies using only the sequenced reads and the assembly as input and it is revealed that variance in the quality of the input data explains 43% of the variance inThe quality of published de noVO transcriptome assembly assemblies.
Posted ContentDOI
TransRate: reference free quality assessment of de-novo transcriptome assemblies
TL;DR: TransRate can accurately evaluate assemblies of conserved and novel RNA molecules of any kind in any species and is more accurate than comparable methods and demonstrates its use on a variety of data.
Journal ArticleDOI
Imaging breast cancer using hyperpolarized carbon-13 MRI.
Ferdia A. Gallagher,Ramona Woitek,Ramona Woitek,Mary A. McLean,Andrew B. Gill,Raquel Manzano Garcia,Elena Provenzano,Frank Riemer,Joshua D. Kaggie,Anita Chhabra,Stephan Ursprung,James T. Grist,Charlie J. Daniels,Fulvio Zaccagna,Marie-Christine Laurent,Matthew Locke,Sarah Hilborne,Amy Frary,Turid Torheim,Chris Boursnell,Amy Schiller,Ilse Patterson,Rhys Slough,Bruno Carmo,Justine Kane,Heather Biggs,Emma Harrison,Surrin S. Deen,Andrew J. Patterson,Titus Lanz,Zoya Kingsbury,Mark T. Ross,Bristi Basu,Richard D. Baird,David J. Lomas,Evis Sala,James Wason,James Wason,Oscar M. Rueda,Suet-Feung Chin,Ian B. Wilkinson,Martin J. Graves,Jean Abraham,Fiona J. Gilbert,Carlos Caldas,Kevin M. Brindle +45 more
TL;DR: Imaging of hyperpolarized [1-13C]pyruvate metabolism in breast cancer is feasible and demonstrated significant intertumoral and intratumoral metabolic heterogeneity, where lactate labeling correlated with MCT1 expression and hypoxia.
Journal ArticleDOI
Transcript residency on ribosomes reveals a key role for the Arabidopsis thaliana bundle sheath in sulfur and glucosinolate metabolism
TL;DR: Insight is provided into the molecular function of this cell type in C3 species Arabidopsis thaliana, and characteristics of BS cells that are probably ancestral to both C3 and C4 plants are identified.