Ciara Marie Kelly

TL;DR: A large-scale, prospective clinical sequencing initiative using a comprehensive assay, MSK-IMPACT, through which tumor and matched normal sequence data from a unique cohort of more than 10,000 patients with advanced cancer are compiled and identified clinically relevant somatic mutations, novel noncoding alterations, and mutational signatures that were shared by common and rare tumor types.

TL;DR: This portion of the NCCN Guidelines discusses general principles for the diagnosis and treatment of retroperitoneal/intra-abdominal STS, outlines treatment recommendations, and reviews the evidence to support the guidelines recommendations.

TL;DR: The panel discussion behind recent important updates to the NCCN Guidelines Insights summary the development of a separate and distinct guideline for gastrointestinal stromal tumors (GISTs), reconception of the management of desmoid tumors, and revision of the principles of radiation therapy for soft tissue sarcomas are summarized.

TL;DR: The past, present, and potential future of functional performance status assessment in an oncology setting is reviewed and the potential ability of electronic activity monitoring systems to provide an objective, accurate measurement of patient functional performance is explored.

TL;DR: Thrombocytopenia, especially ITP, induced by immune checkpoint inhibitors appears to be an uncommon irAE that is manageable with observation in mild cases and/or standard ITP treatment algorithms.