C
Costantino Iadecola
Researcher at Cornell University
Publications - 468
Citations - 59815
Costantino Iadecola is an academic researcher from Cornell University. The author has contributed to research in topics: Stroke & Ischemia. The author has an hindex of 107, co-authored 435 publications receiving 51044 citations. Previous affiliations of Costantino Iadecola include University of Chicago & University of Minnesota.
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Journal ArticleDOI
Pathobiology of ischaemic stroke: an integrated view
TL;DR: This article provides a framework that can be used to generate testable hypotheses and treatment strategies that are linked to the appearance of specific pathophysiological events within the ischaemic brain.
Journal ArticleDOI
Vascular Contributions to Cognitive Impairment and Dementia A Statement for Healthcare Professionals From the American Heart Association/American Stroke Association
Philip B. Gorelick,Angelo Scuteri,Sandra E. Black,Charles DeCarli,Steven M. Greenberg,Costantino Iadecola,Lenore J. Launer,Stéphane Laurent,Oscar L. Lopez,David L. Nyenhuis,Ronald C. Petersen,Julie A. Schneider,Christophe Tzourio,Donna K. Arnett,David A. Bennett,Helena C. Chui,Randall T. Higashida,Ruth Lindquist,Peter M. Nilsson,Gustavo C. Román,Frank W. Sellke,Sudha Seshadri +21 more
TL;DR: This scientific statement provides an overview of the evidence on vascular contributions to cognitive impairment and dementia and provides evidence that subcortical forms of VCI with white matter hyperintensities and small deep infarcts are common and risk markers for VCI are the same as traditional risk factors for stroke.
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Neurovascular regulation in the normal brain and in Alzheimer's disease.
TL;DR: The emerging view is that cerebroVascular dysregulation is a feature not only of cerebrovascular pathologies, such as stroke, but also of neurodegenerative conditions, suchas Alzheimer's disease.
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The immunology of stroke: from mechanisms to translation
TL;DR: Gaining a better understanding of the reciprocal interaction between the immune system and the ischemic brain is essential to harness the full therapeutic potential of the immunology of stroke.
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The Science of Stroke: Mechanisms in Search of Treatments
TL;DR: This review focuses on mechanisms and emerging concepts that drive the science of stroke in a therapeutic direction and poses a number of fundamental questions that may generate new directions for research and possibly new treatments that could reduce the impact of this enormous economic and societal burden.