Cynthia V. Rider

TL;DR: Quantifying the impact of exposure to environmental chemical mixtures is important for identifying risk factors for diseases and developing more targeted public health interventions and future efforts should continue to design and optimize statistical approaches to address questions aboutchemical mixtures in epidemiological studies.

TL;DR: It is argued that a European strategy needs to be set, through stakeholder engagement, for the governance of combined exposure to multiple chemicals and mixtures, as well as research to address regulatory and policy needs.

TL;DR: Animal and human data indicate that repeated oral administration of bolus doses of GTE during fasting significantly increases bioavailability of catechins, specifically EGCG, possibly involving saturation of first-pass elimination mechanisms.

TL;DR: The objective of the current study was to test whether a mixture model of dose addition based on the fetal T production data of individual phthalates would predict the effects of a 5 phthalate mixture on androgen-sensitive postnatal male reproductive tract development and to determine the biological relevance of the reductions in fetal T to induce abnormal postnatal reproductive tractDevelopment.

TL;DR: Addressing the challenges associated with botanical dietary supplement safety is a global effort requiring coordination between numerous stakeholders, including researchers, suppliers, manufacturers, and regulators, all of whom play a role in ensuring that high quality products are available on the market.