Daniel Menezes Souza

TL;DR: The data demonstrated that vaccination with a single dose of LdCen(-/-) (without any adjuvant) resulted in the reduction of up to 87.3% of parasite burden after 18 months of virulent challenge, comparable to those obtained with commercially available vaccine in Brazil (Leishmune(®).

TL;DR: The conjunctival swab is a suitable clinical sample for qualitative molecular diagnosis of CVL and the qPCR results emphasized the role of dogs, particularly asymptomatic dogs, as reservoirs for CVL because of the high cutaneous parasite loads.

TL;DR: This work establishes the therapeutic benefit of SbL8/HePC association by oral route in a CL model and constitutes an important step towards the development of new orally active drug combination.

TL;DR: An extensive analysis of the popularity dynamics of Foursquare tips using a large dataset containing over 10 million tips and 9 million likes posted by over 13,5 million users finds that the social network of the user who posted the tip plays an important role on the tip popularity throughout its lifetime, but particularly at earlier periods after posting time.

TL;DR: The antileishmanial activity of fullerol was reported for the first time and an innovative approach for treatment of VL based on the association of this nanostructure with liposomes is introduced.