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Daniel R. Boue

Researcher at Nationwide Children's Hospital

Publications -  66
Citations -  1294

Daniel R. Boue is an academic researcher from Nationwide Children's Hospital. The author has contributed to research in topics: Medicine & Biology. The author has an hindex of 17, co-authored 49 publications receiving 983 citations. Previous affiliations of Daniel R. Boue include Boston Children's Hospital & Ohio State University.

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Long-term enhancement of skeletal muscle mass and strength by single gene administration of myostatin inhibitors

TL;DR: A one-time gene administration of myostatin-inhibitor-proteins is described to enhance muscle mass and strength in normal and dystrophic mouse models for >2 years, even when delivered in aged animals.
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Alterations in ALK/ROS1/NTRK/MET drive a group of infantile hemispheric gliomas

Ana Guerreiro Stucklin, +65 more
TL;DR: It is concluded that infant gliomas comprise 3 subgroups, justifying the need for specialized therapeutic strategies and revealing genetic alterations which may offer therapeutic opportunities.
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The Congenital Muscular Dystrophies: Recent Advances and Molecular Insights

TL;DR: In muscle diseases with overlapping pathological features, such as CMD, careful attention to the clinical clues can help guide the battery of immunostains necessary to target an unequivocal diagnosis.
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Survivin, Survivin-2B, and Survivin-deItaEx3 expression in medulloblastoma: biologic markers of tumour morphology and clinical outcome.

TL;DR: A role for Survivin as a marker of tumour morphology and clinical outcome in medulloblastoma is demonstrated and Survivin may be a promising future prognostic tool and potential biologic target in this malignancy.
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Outcomes of BRAF V600E pediatric gliomas treated with targeted BRAF inhibition

Liana Nobre, +74 more
TL;DR: Use of BRAF inhibition results in robust and durable responses in BRAF V600E-mutated PLGG, and prospective studies are required to determine long-term survival and functional outcomes with BRAF inhibitor therapy in childhood gliomas.