D
Daniela Weber
Researcher at University of Regensburg
Publications - 93
Citations - 3482
Daniela Weber is an academic researcher from University of Regensburg. The author has contributed to research in topics: Transplantation & Myeloid leukemia. The author has an hindex of 28, co-authored 76 publications receiving 2385 citations.
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Journal ArticleDOI
Intestinal Microbiota and Relapse After Hematopoietic-Cell Transplantation
Jonathan U. Peled,Sean M. Devlin,Anna Staffas,Melissa Lumish,Raya Khanin,Eric R. Littmann,Lilan Ling,Satyajit Kosuri,Molly Maloy,John B. Slingerland,Katya F. Ahr,Kori A. Porosnicu Rodriguez,Yusuke Shono,Ann E. Slingerland,Melissa D. Docampo,Anthony D. Sung,Daniela Weber,Amin M. Alousi,Boglarka Gyurkocza,Doris M. Ponce,Juliet N. Barker,Miguel-Angel Perales,Sergio Giralt,Ying Taur,Eric G. Pamer,Robert R. Jenq,Marcel R.M. van den Brink +26 more
TL;DR: In this article, the authors examined the relationship between abundance of microbiota species or groups of related species and relapse/progression of disease during 2 years of follow-up time after allogeneic hematopoietic-cell transplantation (allo-HCT) by using cause-specific proportional hazards in a retrospective discovery-validation cohort study.
Journal ArticleDOI
Midostaurin added to chemotherapy and continued single-agent maintenance therapy in acute myeloid leukemia with FLT3-ITD.
Richard F. Schlenk,Richard F. Schlenk,Daniela Weber,Walter Fiedler,Helmut R. Salih,Gerald Wulf,Hans Salwender,Thomas Schroeder,Thomas Kindler,Michael Lübbert,Dominik Wolf,Jörg Westermann,Doris Kraemer,Katharina Götze,Heinz-August Horst,Jürgen Krauter,Michael Girschikofsky,Mark Ringhoffer,Thomas Südhoff,Gerhard Held,Hans-Günter Derigs,Roland Schroers,Richard Greil,Martin Grießhammer,Elisabeth Lange,Alexander Burchardt,Uwe M. Martens,Bernd Hertenstein,Lore Marretta,Michael Heuser,Felicitas Thol,Verena I. Gaidzik,Wolfgang Herr,Julia Krzykalla,Axel Benner,Konstanze Döhner,Arnold Ganser,Peter Paschka,Hartmut Döhner +38 more
TL;DR: A phase 2 hypothesis-generating trial to determine whether the addition of the multitargeted kinase inhibitor midostaurin to intensive chemotherapy followed by allogeneic hematopoietic cell transplantation and single-agent maintenance therapy of 12 months is feasible and favorably influences event-free survival (EFS) compared with historical controls.
Journal ArticleDOI
RUNX1 mutations in acute myeloid leukemia are associated with distinct clinico-pathologic and genetic features.
Verena I. Gaidzik,Veronica Teleanu,Elli Papaemmanuil,Daniela Weber,Peter Paschka,J Hahn,T Wallrabenstein,B Kolbinger,Claus-Henning Köhne,Heinz-August Horst,Peter Brossart,Gerhard Held,Andrea Kündgen,Mark Ringhoffer,Katharina Götze,Mathias J. Rummel,Moritz Gerstung,Peter J. Campbell,Johann M. Kraus,Hans A. Kestler,Felicitas Thol,Michael Heuser,Brigitte Schlegelberger,Arnold Ganser,Lars Bullinger,Richard F. Schlenk,K Döhner,Hartmut Döhner +27 more
TL;DR: It is concluded that RUNX1-mutated AML is associated with a complex mutation cluster and is correlated with distinct clinico-pathologic features and inferior prognosis.
Journal ArticleDOI
Lactose drives Enterococcus expansion to promote graft-versus-host disease.
C. K. Stein-Thoeringer,C. K. Stein-Thoeringer,C. K. Stein-Thoeringer,K. B. Nichols,K. B. Nichols,A. Lazrak,A. Lazrak,Melissa D. Docampo,Melissa D. Docampo,Ann E. Slingerland,Ann E. Slingerland,J. B. Slingerland,J. B. Slingerland,Annelie Clurman,G. Armijo,G. Armijo,Antonio L.C. Gomes,Antonio L.C. Gomes,Yusuke Shono,Yusuke Shono,Anna Staffas,Anna Staffas,M. Burgos da Silva,M. Burgos da Silva,Sean M. Devlin,Kate A. Markey,Kate A. Markey,D. Bajic,R. Pinedo,A. Tsakmaklis,Eric R. Littmann,Eric R. Littmann,Alessandro Pastore,Ying Taur,Sebastien Monette,M. E. Arcila,Amanda J. Pickard,Molly Maloy,Roberta J. Wright,Luigi A Amoretti,Emily Fontana,D. Pham,M. A. Jamal,Daniela Weber,Anthony D. Sung,Daigo Hashimoto,C. Scheid,Joao B. Xavier,Julia A. Messina,Kristi Romero,Meagan V. Lew,Amy Bush,Lauren Bohannon,Koji Hayasaka,Yuta Hasegawa,M. J. G. T. Vehreschild,M. J. G. T. Vehreschild,Justin R. Cross,Doris M. Ponce,Doris M. Ponce,Miguel-Angel Perales,Miguel-Angel Perales,Sergio Giralt,Sergio Giralt,Robert R. Jenq,Takanori Teshima,Ernst Holler,Nelson J. Chao,Eric G. Pamer,Eric G. Pamer,Eric G. Pamer,Jonathan U. Peled,Jonathan U. Peled,M.R.M. van den Brink,M.R.M. van den Brink +74 more
TL;DR: Lactose is reported as a common nutrient that drives expansion of a commensal bacterium that exacerbates an intestinal and systemic inflammatory disease and is associated with graft-versus-host disease (GVHD) and mortality in patients.
Journal ArticleDOI
Adjusting microbiome profiles for differences in microbial load by spike-in bacteria
Frank Stämmler,Joachim Gläsner,Andreas Hiergeist,Ernst Holler,Daniela Weber,Peter J. Oefner,André Gessner,Rainer Spang +7 more
TL;DR: Exogenous spike-in bacteria in gut microbiome studies enable estimation of ratios of absolute OTU abundances, providing novel insights into the structure and the dynamics of intestinal microbiomes.