Darcy F. de Almeida

TL;DR: Genomic comparisons revealed that reduction in genome size implied loss of redundant metabolic pathways, with maintenance of alternative routes in different species, and indicated a likely transfer event of hemagglutinin-coding DNA sequences from M. gallisepticum to M. synoviae.

TL;DR: The complete genome sequence reveals extensive alternative pathways for energy generation, complex and extensive systems for stress adaptation and motility, and widespread utilization of quorum sensing for control of inducible systems, all of which underpin the versatility and adaptability of the organism.

TL;DR: In contrast to the previous model, a tight dimer rather than a monomer is the functional repressor, and the LexA dimer only loses its ability to recognize a specific DNA sequence by RecA-induced autoproteolysis.

TL;DR: A web-based software suite, SABIA (System for Automated Bacterial Integrated Annotation), is described that provides a comprehensive computational support for the assembly and annotation of whole bacterial genomes from the data derived from sequencing projects.

TL;DR: Systemic and mucosal antibody responses against both the major subunit of colonization factor antigen I and the somatic lipopolysaccharide expressed by recombinant bivalent Salmonella vaccine strains were significantly enhanced by coadministration of a detoxified derivative with preserved adjuvant effects of the ETEC heat-labile toxin, LT(R192G).