Ebert Seixas Hanna

TL;DR: The complete genome sequence reveals extensive alternative pathways for energy generation, complex and extensive systems for stress adaptation and motility, and widespread utilization of quorum sensing for control of inducible systems, all of which underpin the versatility and adaptability of the organism.

TL;DR: Genomic data on the type strain ATCC 12472(T) has provided a comprehensive basis for detailed studies of pathogenicity, virulence and drug resistance genes, and a large number of open reading frames associated with various mechanisms of drug resistance were found, comprising a remarkable feature of this organism.

TL;DR: It is shown that immunization induced the production of high levels of specific IgG and IgA antibodies and promoted reduction in the fecal shedding of EHEC after challenge and the live recombinant vaccine reported herein may contribute to the efforts of reducing animal intestinal mucosa colonization.

TL;DR: It is proposed that rPCN binds to N-glycans on TLRs, triggers regulated Th1 immunity, and exerts a therapeutic effect against P. brasiliensis infection, and acts as a TLR agonist.

TL;DR: It is observed that injection of paracoccin three days before challenge was the most efficient administration protocol, as the induced Th1 immunity was balanced by high levels of pulmonary IL-10, which may prevent the tissue damage caused by exacerbated inflammation.