D
David A. Johnston
Researcher at Natural History Museum
Publications - 33
Citations - 2860
David A. Johnston is an academic researcher from Natural History Museum. The author has contributed to research in topics: Schistosoma mansoni & Gene. The author has an hindex of 22, co-authored 33 publications receiving 2706 citations. Previous affiliations of David A. Johnston include University of Southampton & British Museum.
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Journal ArticleDOI
The genome of the blood fluke Schistosoma mansoni
Matthew Berriman,Brian J. Haas,Brian J. Haas,Philip T. LoVerde,R. Alan Wilson,Gary P. Dillon,Gustavo C. Cerqueira,Susan T. Mashiyama,Bissan Al-Lazikani,Luiza F. Andrade,Peter D. Ashton,Martin Aslett,Daniella Castanheira Bartholomeu,Daniella Castanheira Bartholomeu,Gaëlle Blandin,Conor R. Caffrey,Avril Coghlan,Richard M.R. Coulson,Tim A. Day,Arthur L. Delcher,Ricardo DeMarco,Ricardo DeMarco,Appoliniare Djikeng,Tina Eyre,John Gamble,Elodie Ghedin,Elodie Ghedin,Yong-Hong Gu,Christiane Hertz-Fowler,Hirohisha Hirai,Yuriko Hirai,Robin Houston,Alasdair Ivens,David A. Johnston,David A. Johnston,Daniela R. Lacerda,Daniela R. Lacerda,Camila D. S. Macedo,Paul McVeigh,Zemin Ning,Guilherme Oliveira,John P. Overington,Julian Parkhill,Mihaela Pertea,Raymond J. Pierce,Anna V. Protasio,Michael A. Quail,Marie-Adèle Rajandream,Jane Rogers,Mohammed Sajid,Steven L. Salzberg,Mario Stanke,Adrian Tivey,Owen White,Owen White,David L. Williams,David L. Williams,Jennifer R. Wortman,Jennifer R. Wortman,Wenjie Wu,Mostafa Zamanian,Adhemar Zerlotini,Claire M. Fraser-Liggett,Claire M. Fraser-Liggett,Barclay G. Barrell,Najib M. El-Sayed,Najib M. El-Sayed +66 more
TL;DR: Analysis of the 363 megabase nuclear genome of the blood fluke, the first sequenced flatworm, and a representative of the Lophotrochozoa offers insights into early events in the evolution of the animals, including the development of a body pattern with bilateral symmetry, and theDevelopment of tissues into organs.
Journal ArticleDOI
The phylogeny of the Schistosomatidae based on three genes with emphasis on the interrelationships of Schistosoma Weinland, 1858.
Anne E. Lockyer,Peter D. Olson,Pia Ostergaard,David Rollinson,David A. Johnston,S. W. Attwood,Vr Southgate,Petr Horák,S. D. Snyder,Thanh Hoa Le,Takeshi Agatsuma,Donald P. McManus,A. C. Carmichael,S. Naem,D. T. J. Littlewood +14 more
TL;DR: The principal findings are that Ornithobilharzia and AustrobilHarzia form a sister group to the Schistosoma; mammalian schistosomes appear paraphyletic and 2 TrichobilharZia species, T. ocellata and T. szidati, seem to be synonymous.
Journal ArticleDOI
The Schistosoma mansoni soluble proteome: a comparison across four life-cycle stages.
TL;DR: The similarity in composition between the four preparations means that they are unlikely to discriminate adequately between immune responses to different life-cycle stages and argues strongly for the need to identify true stage-specific marker proteins.
Journal ArticleDOI
The complete mitochondrial genomes of Schistosoma haematobium and Schistosoma spindale and the evolutionary history of mitochondrial genome changes among parasitic flatworms.
TL;DR: Results confirm a major gene order rearrangement among schistosomes in all traditional Schistosoma species groups other than SchistOSoma japonicum; i.e., species groups S. mansoni, S. haematobium, and S. indicum and lend support to the 'out of Asia' (East and Southeast Asia) hypothesis for Schistsoma.
Journal ArticleDOI
Identification of Schistosoma mansoni gender-associated gene transcripts by cDNA microarray profiling.
TL;DR: This study shows how molecules involved in sexual biology can be rapidly identified in cDNA microarrays and expands the list of S. mansoni gender-associated gene transcripts from all previous studies by a factor of two.