David S. Wishart

TL;DR: The first publically available interlaboratory ring trial for standardized bile acids quantification in human and mouse plasma samples showed very good analytical performance, within acceptance criteria typically applied in the preclinical environment, suitable for standardized quantitative bile acid analysis and the establishment of reference values.

TL;DR: This work has identified that shaking alone causes the conversion of recombinant PrP to β-sheet rich oligomers and fibrils at near physiological pH and temperature and proposed that this method of conversion provides a robust, reproducible and easily accessible model for scrapie-like amyloid formation.

TL;DR: Findings highlight that gluten-free flours are able to deliver bioaccessible polyphenols to the colon, and a decreasing trend was observed for antioxidant activities moving from digested to faecal fermented samples.

TL;DR: The NOMS is able to sense GC peaks from derivatized metabolites at physiological concentrations, an important milestone for small-molecule quantitation assays in next generation metabolite analyses for applications such as disease diagnosis and personalized medicine.

TL;DR: In this population of advanced cancer patients, lean and fat mass variation could be effectively predicted using urinary metabolites, suggesting a potential role for metabolomics in body composition research.